Objective Autoantibodies have been demonstrated in single serum samples from healthy
subjects up to 10 years before they developed rheumatoid arthritis (RA). However, the time …

To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

PURPOSE: To compare the effect of delayed and early treatment strategies on disease
outcome in patients with rheumatoid arthritis. SUBJECTS AND METHODS: Between 1993 and …

Ankylosing spondylitis is a common, highly heritable inflammatory arthritis affecting
primarily the spine and pelvis. In addition to HLA-B*27 alleles, 12 loci have previously been …

OBJECTIVE: To evaluate the cardiovascular risk profile of spondylarthropathy patients,
particularly ankylosing spondylitis and psoriatic arthritis. METHODS: A Pubmed literature search …

To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis
of two published genome-wide association (GWA) studies totaling 3,393 cases and …

To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P < 0.001 in a published meta-analysis of RA genome-wide …

Background Anti-citrullinated protein antibodies (ACPA) are associated with increased risk
for rheumatoid arthritis. Objective To investigate the effect of the presence and levels of ACPA …

… /van der Heijde score and the three antibody tests. The non-completers had a higher median
Sharp/van der Heijde … of patients with a high Sharp/van der Heijde score at baseline, and a …

Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which
HLA-B*27 is the major genetic risk factor, although its role in the aetiology of AS remains …