Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity

RM Talaat, SF Mohamed, IH Bassyouni, AA Raouf - Cytokine, 2015 - Elsevier
Aim Imbalance of T-helper-cell (TH) subsets (TH1/TH2/TH17) and regulatory T-cells (Tregs)
is suggested to contribute to the pathogenesis of Systemic lupus erythematosus (SLE). …

Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl in patients with systemic lupus erythematosus and …

TA Gheita, IH Bassyouni, RH Bassyouni - Journal of clinical immunology, 2012 - Springer
Purpose The aim of the present study was to investigate plasma concentrations of Gas6 and
its soluble tyrosine kinase receptor sAxl in Systemic lupus erythematosus (SLE) and …

Polymorphisms of interleukin 6 and interleukin 10 in Egyptian people with Behcet's disease

RM Talaat, ME Ashour, IH Bassyouni, AA Raouf - Immunobiology, 2014 - Elsevier
Cytokines play critical roles in the pathogenesis of Behçet's disease (BD). They mediated
many of the effectors and regulatory functions of immune and inflammatory responses. Many …

Upregulation of miR-221/222 expression in rheumatoid arthritis (RA) patients: correlation with disease activity

AS Abo ElAtta, YBM Ali, IH Bassyouni… - Clinical and Experimental …, 2019 - Springer
miRNAs are noncoding RNA that play a critical role as fine regulators of gene expression at
the posttranscriptional level within cells in numerous autoimmune diseases. miR-221/222 …

[HTML][HTML] The association between vitamin D levels and oxidative stress markers in Egyptian Behcet's disease patients

…, FA Ibrahim, A El Gendy, IH Bassyouni… - Orphanet Journal of …, 2022 - Springer
Background Oxidative stress is postulated to have a major role in the pathophysiology of
Bechet’s Disease (BD). Growing evidence suggests that vitamin D has important roles in …

Crosstalk between miR-146a and pro-inflammatory cytokines in patients with systemic lupus erythematosus

…, SA El-Masry, IH Bassyouni… - International …, 2023 - journals.sagepub.com
microRNA-146a (miR-146a) plays an essential role in immune anomalies and organ injury
of systemic lupus erythematosus (SLE) by regulating the disease’s inflammation and …

Enthesitis and related changes in the knees in seronegative spondyloarthropathies and skin psoriasis: magnetic resonance imaging case-control study

Y Emad, Y Ragab, I Bassyouni, O Moawayh… - The Journal of …, 2010 - jrheum.org
Objective. To describe enhanced magnetic resonance imaging (MRI) features and characteristic
entheseal changes in the knees in patients with seronegative spondyloarthropathy (SpA…

Clinical association of a soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in patients with systemic lupus erythematosus

IH Bassyouni, S Fawzi, TA Gheita… - Immunological …, 2017 - Taylor & Francis
A triggering receptor expressed on myeloid cells-1 (TREM-1) is a member of the immunoglobulin
superfamily with an established role in innate and adaptive immune response. We …

[HTML][HTML] mir-146a genetic polymorphisms in systemic lupus erythematosus patients: correlation with disease manifestations

…, YBM Ali, SA El-Masry, IH Bassyouni… - Non-coding RNA …, 2022 - Elsevier
This study aimed to investigate the genetic polymorphisms of miR-146a SNPs (rs2910164,
rs57095329, and rs2431697) in systemic lupus erythematosus (SLE) patients and their …

IL-17, IL-10, IL-6, and IFN-γ in Egyptian Behçet's disease: correlation with clinical manifestations

RM Talaat, H Sibaii, IH Bassyouni… - European Cytokine …, 2019 - Springer
There are a limited number of studies that report the polarization of the immune system toward
the production of T helper 1 (Th1), Th2, or Th17-type cytokines in patients with Behçet’s …