The recent unraveling of structures of genes for the gonadotropin subunits and gonadotropin
receptors has provided reproductive endocrinologists with new tools to study normal and …

The recent onslaught of mass spectrometry (MS) to measurements of steroid hormones,
including demands that they should be the only acceptable method, has confused clinicians and …

Spermatogenesis and folliculogenesis involve cell–cell interactions and gene expression
orchestrated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH). FSH …

Background The association between aging-related testosterone deficiency and late-onset
hypogonadism in men remains a controversial concept. We sought evidence-based criteria …

Context: The cause of declining testosterone (T) in aging men and their relationships with
risk factors are unclear. Objective: The objective of the study was to investigate the …

Gonadal function is controlled by the two pituitary gonadotropins, luteinizing hormone (LH)
and follicle-stimulating hormone (FSH). While LH mainly regulates gonadal steroidogenesis, …

Context: The diagnosis of late-onset hypogonadism (LOH) in older men with age-related
declines in testosterone (T) is currently not well characterized. Objective: Our objective was to …

Introduction Limited information is available concerning the general and sexual health status
of European men. Aim To investigate the age-related changes in general and sexual health …

Context: Late-onset hypogonadism (LOH) has been defined as a syndrome in middle-aged
and elderly men reporting symptoms in the presence of low testosterone (T). Objective: The …

Objective Interrelationships between hormones of the hypothalamic–pituitary–testicular (HPT)
axis, hypogonadism, vitamin D and seasonality remain poorly defined. We investigated …