[HTML][HTML] Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
S Sun, CCT Sprenger, RL Vessella… - The Journal of …, 2010 - Am Soc Clin Investig
Progression of prostate cancer following castration is associated with increased androgen
receptor (AR) expression and signaling despite AR blockade. Recent studies suggest that …
receptor (AR) expression and signaling despite AR blockade. Recent studies suggest that …
Tumor microenvironment characterization in gastric cancer identifies prognostic and immunotherapeutically relevant gene signatures
D Zeng, M Li, R Zhou, J Zhang, H Sun, M Shi… - Cancer immunology …, 2019 - AACR
Tumor microenvironment (TME) cells constitute a vital element of tumor tissue. Increasing
evidence has elucidated their clinicopathologic significance in predicting outcomes and …
evidence has elucidated their clinicopathologic significance in predicting outcomes and …
Efficacy of systemic treatments for moderate to severe plaque psoriasis: systematic review and meta-analysis
Aims: To compare the efficacy of psoriasis treatments through a systematic literature review
and meta-analysis. Methods: Randomized controlled trials evaluating the Psoriasis Area and …
and meta-analysis. Methods: Randomized controlled trials evaluating the Psoriasis Area and …
Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer
…, AT Le, A Truini, MB Nilsson, H Sun… - Nature medicine, 2018 - nature.com
Although most activating mutations of epidermal growth factor receptor (EGFR)-mutant non–small
cell lung cancers (NSCLCs) are sensitive to available EGFR tyrosine kinase inhibitors (…
cell lung cancers (NSCLCs) are sensitive to available EGFR tyrosine kinase inhibitors (…
Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC
…, E Roarty, W Rinsurongkawong, M Tang, H Sun… - Clinical Cancer …, 2018 - AACR
Purpose: Osimertinib was initially approved for T790M-positive non–small cell lung cancer (NSCLC)
and, more recently, for first-line treatment of EGFR-mutant NSCLC. However, …
and, more recently, for first-line treatment of EGFR-mutant NSCLC. However, …
[HTML][HTML] Functional biomaterials for comprehensive periodontitis therapy
J Luan, R Li, W Xu, H Sun, Q Li, D Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Periodontitis is an inflammatory disease caused by bacterial infection directly, and the
dysregulation of host immune-inflammatory response finally destroys periodontal tissues. Current …
dysregulation of host immune-inflammatory response finally destroys periodontal tissues. Current …
[HTML][HTML] Immune cell infiltration as a biomarker for the diagnosis and prognosis of stage I–III colon cancer
R Zhou, J Zhang, D Zeng, H Sun, X Rong, M Shi… - Cancer immunology …, 2019 - Springer
Tumour-infiltrating immune cells are a source of important prognostic information for patients
with resectable colon cancer. We developed a novel immune model based on systematic …
with resectable colon cancer. We developed a novel immune model based on systematic …
[HTML][HTML] Tumor microenvironment evaluation promotes precise checkpoint immunotherapy of advanced gastric cancer
…, N Huang, J Wu, X Rong, L Sun, H Sun… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Durable efficacy of immune checkpoint blockade (ICB) occurred in a small
number of patients with metastatic gastric cancer (mGC) and the determinant biomarker of …
number of patients with metastatic gastric cancer (mGC) and the determinant biomarker of …
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components
MB Nilsson, H Sun, J Robichaux, M Pfeifer… - Science translational …, 2020 - science.org
Acquired resistance to tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR)
remains a clinical challenge. Especially challenging are cases in which resistance …
remains a clinical challenge. Especially challenging are cases in which resistance …
[HTML][HTML] Macrophage correlates with immunophenotype and predicts anti-PD-L1 response of urothelial cancer
…, R Zhou, X Fan, G Wang, Y Huang, J Wu, H Sun… - Theranostics, 2020 - ncbi.nlm.nih.gov
Immune-checkpoint blockades (ICBs) have been routinely implemented to treat metastatic
urothelial cancer (mUC), whereas robust biomarkers are urgently warranted. Herein, we …
urothelial cancer (mUC), whereas robust biomarkers are urgently warranted. Herein, we …