Survival rates are improving following cancer therapy for childhood brain tumours. There is
therefore a growing cohort of survivors at risk of late effects of cancer therapy. Endocrine …

OBJECTIVE: Chronic relapsing multifocal osteomyelitis (CRMO) results in significant
morbidity, especially in those with vertebral collapse. Symptomatic benefit with intravenous …

Final height (FH) outcome is important in survivors of childhood brain tumors. GH replacement
is indicated in those found to be GH deficient (GHD). More recently, GnRH analogs (…

Background Congenital adrenal hyperplasia ( CAH ) has implications throughout a patient's
life. The challenges of organizing transition from paediatric to adult care in endocrinology …

The lack of focus on young people as a group with particular healthcare needs in medical
training and the health service underpins the difficulty that we have experienced as a …

Context Androgen excess in women is predominantly due to underlying polycystic ovary
syndrome (PCOS). However, there is a lack of clarity regarding patterns and severity of …

The past 30 years have seen a great improvement in survival of children and young adults
treated for cancer. Cancer treatment can put patients at risk of health problems that can …

Childhood survivors of cancer are prone to a number of adverse sequelae related to the
therapeutic interventions undertaken to achieve remission. The endocrine system is frequently …

Context The 250-μg short Synacthen (corticotropin) test (SST) is the most commonly used
tool to assess hypothalamo-pituitary-adrenal (HPA) axis function. There are many potentially …

Endocrine disorders in survivors of childhood, adolescent, and young adult (CAYA) cancers
are associated with substantial adverse physical and psychosocial effects. To improve …