Background Glucosamine and chondroitin sulfate are used to treat osteoarthritis. The
multicenter, double-blind, placebo- and celecoxib-controlled Glucosamine/chondroitin Arthritis …

Context Idiopathic sudden sensorineural hearing loss has been treated with oral corticosteroids
for more than 30 years. Recently, many patients' symptoms have been managed with …

Objective Osteoarthritis (OA) of the knee causes significant morbidity and current medical
treatment is limited to symptom relief, while therapies able to slow structural damage remain …

Background Knee osteoarthritis (OA) is a major cause of pain and functional limitation in
older adults, yet longer-term studies of medical treatment of OA are limited. Objective To …

We recently showed that losartan and paricalcitol are synergistic in the treatment of diabetic
nephropathy in a model of type 1 diabetes. To test this strategy in a model of type 2 diabetes, …

Carbonic acid and liquid hot water pretreatments were applied to corn stover. Temperatures
ranged from 180 to 220 C; reaction times varied between 2 and 32 min and prereaction …

Importance Benign vocal fold nodules affect 12% to 22% of the pediatric population, and 95%
of otolaryngologists recommend voice therapy as treatment. However, no randomized …

Methods were developed to systematically screen different polymer–surfactant combinations
for the purpose of enhancing amorphous active pharmaceutical ingredient (API) solubility …

Objective. To define pain and physical function cutpoints that would, coupled with structural
severity, define a surrogate measure of “need for joint replacement surgery,” for use as an …

With the prevalence of therapeutic monoclonal antibodies (mAbs) in the biopharmaceutical
industry, the use of mammalian cell culture systems, particularly Chinese hamster ovary (…