User profiles for HARLAN SAYLES

Harlan Sayles

University of Nebraska Medical Center
Verified email at unmc.edu
Cited by 4444

Porphyromonas gingivalis and disease‐related autoantibodies in individuals at increased risk of rheumatoid arthritis

…, JB Payne, JR O'Dell, F Yu, H Sayles… - Arthritis & …, 2012 - Wiley Online Library
Objective To examine the relationship of Porphyromonas gingivalis to the presence of
autoantibodies in individuals at risk of rheumatoid arthritis (RA). Methods Study participants …

Rheumatoid factor as a potentiator of anti–citrullinated protein antibody–mediated inflammation in rheumatoid arthritis

…, GM Thiele, K Michaud, H Sayles… - Arthritis & …, 2014 - Wiley Online Library
Objective The co‐occurrence of rheumatoid factor (RF) and anti–citrullinated protein antibody
(ACPA) positivity in rheumatoid arthritis (RA) is well described. However, the mechanisms …

Validation of the rheumatic disease comorbidity index

BR England, H Sayles, TR Mikuls… - Arthritis care & …, 2015 - Wiley Online Library
Objective There is no consensus on which comorbidity index is optimal for rheumatic health
outcomes research. We compared a new Rheumatic Disease Comorbidity Index (RDCI) with …

Malondialdehyde‐acetaldehyde adducts and anti–malondialdehyde‐acetaldehyde antibodies in rheumatoid arthritis

…, D Benissan‐Messan, H Sayles… - Arthritis & …, 2015 - Wiley Online Library
Objective Malondialdehyde‐acetaldehyde (MAA) adducts are a product of oxidative stress
associated with tolerance loss in several disease states. This study was undertaken to …

Cause‐specific mortality in male US veterans with rheumatoid arthritis

BR England, H Sayles, K Michaud… - Arthritis care & …, 2016 - Wiley Online Library
Objective There has been limited investigation into cause‐specific mortality and the associated
risk factors in men with rheumatoid arthritis (RA). We investigated all‐cause and cause‐…

Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry

TR Mikuls, BT Fay, K Michaud, H Sayles… - …, 2011 - academic.oup.com
Objectives. To examine the all-cause mortality rate and factors associated with mortality in
US veteran men with RA. Methods. Men with RA were enrolled and followed until death or …

Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients

J Williams, HR Sayles, JL Meza, P Sayre… - …, 2013 - Future Medicine
Aim: To gauge patient interest in receiving long-acting injectable nanoformulated
antiretroviral therapy. Methods: Four hundred adult HIV-infected patients currently prescribed …

COVID‐19 patients with documented alcohol use disorder or alcohol‐related complications are more likely to be hospitalized and have higher all‐cause mortality

KL Bailey, H Sayles, J Campbell… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background Coronavirus Disease 2019 (COVID‐19) has affected every country globally,
with hundreds of millions of people infected with the SARS‐CoV‐2 virus and over 6 million …

Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis

…, X Jiang, TR Mikuls, JB Payne, HR Sayles… - Annals of the …, 2016 - ard.bmj.com
Objectives We investigated whether citrullinated tenascin-C (cTNC), an extracellular matrix
protein expressed at high levels in the joints of patients with rheumatoid arthritis (RA), is a …

Prevention of depression with escitalopram in patients undergoing treatment for head and neck cancer: randomized, double-blind, placebo-controlled clinical trial

…, D Bessette, KK Schmid, H Sayles… - … –Head & Neck …, 2013 - jamanetwork.com
Importance Major depressive disorder develops in up to half the patients undergoing
treatment for head and neck cancer, resulting in significant morbidity; therefore, preventing …