User profiles for Giovanni Candiano

Giovanni Candiano

Istituto Giannina Gaslini IRCCS - Genova
Verified email at ospedale-gaslini.ge.it
Cited by 9341

Blue silver: a very sensitive colloidal Coomassie G‐250 staining for proteome analysis

G Candiano, M Bruschi, L Musante, L Santucci… - …, 2004 - Wiley Online Library
A modified Neuhoff's colloidal Coomassie Blue G‐250 stain is reported, dubbed “blue silver”
on account of its considerably higher sensitivity, approaching the one of conventional silver …

Autoimmunity in membranous nephropathy targets aldose reductase and SOD2

M Prunotto, ML Carnevali, G Candiano… - Journal of the …, 2010 - journals.lww.com
Glomerular targets of autoimmunity in human membranous nephropathy are poorly understood.
Here, we used a combined proteomic approach to identify specific antibodies against …

[HTML][HTML] Neutrophil extracellular traps (NET) induced by different stimuli: A comparative proteomic analysis

A Petretto, M Bruschi, F Pratesi, C Croia, G Candiano… - PloS one, 2019 - journals.plos.org
Neutrophil extracellular traps (NET) formation is part of the neutrophil response to infections,
but excessive or inappropriate NETosis may trigger the production of autoantibodies and …

Prevalence, genetics, and clinical features of patients carrying podocin mutations in steroid-resistant nonfamilial focal segmental glomerulosclerosis

…, M Carraro, C Zennaro, G Candiano… - Journal of the …, 2001 - journals.lww.com
ABSTRACT. Podocin mutations (NPHS2 gene) are responsible for the autosomal recessive
form of steroid-resistant nephrotic syndrome. As a result of a screening for these gene …

Coexistence of different circulating anti-podocyte antibodies in membranous nephropathy

C Murtas, M Bruschi, G Candiano… - Clinical Journal of the …, 2012 - journals.lww.com
Results IgG 4 was the most common isotype for all antibodies; IgG 1 and IgG 3 were nearly
negligible. IgG 4 levels were positive in a significant proportion of MN patients (AR, 34%; …

Direct characterization of target podocyte antigens and auto-antibodies in human membranous glomerulonephritis: Alfa-enolase and borderline antigens

M Bruschi, ML Carnevali, C Murtas, G Candiano… - Journal of …, 2011 - Elsevier
The identification of glomerular auto-antigens in idiopathic human membranous
glomerulonephritis (MGN) is a crucial step towards the definition of the mechanisms of the disease. …

Repetitive fragmentation products of albumin and α1-antitrypsin in glomerular diseases associated with nephrotic syndrome

G Candiano, L Musante, M Bruschi… - Journal of the …, 2006 - journals.lww.com
Even if nephrotic syndrome is characterized by massive urinary loss of major plasma proteins,
a clear structural characterization based on proteomics has never been reported. Urine …

Glomerular Autoimmune Multicomponents of Human Lupus Nephritis In Vivo: α:-Enolase and Annexin AI

…, F Scolari, A Martini, G Candiano… - Journal of the …, 2014 - journals.lww.com
Renal targets of autoimmunity in human lupus nephritis (LN) are unknown. We sought to
identify autoantibodies and glomerular target antigens in renal biopsy samples from patients …

Neutrophil extracellular traps profiles in patients with incident systemic lupus erythematosus and lupus nephritis

…, A Tincani, P Cravedi, S Volpi, G Candiano… - The Journal of …, 2020 - jrheum.org
Objective. Neutrophil extracellular traps (NET) expose modified antigens for autoantibodies
in vasculitis. Little is known about levels and removal pathways of NET in systemic lupus …

[HTML][HTML] Oxidative stress as a primary risk factor for brain damage in preterm newborns

I Panfoli, G Candiano, M Malova, L De Angelis… - Frontiers in …, 2018 - frontiersin.org
The risk of oxidative stress is high in preterm newborns. Room air exposure of an organism
primed to develop in a hypoxic environment, lacking antioxidant defenses, and subjected to …