Outcome and prognostic factors during the course of primary small-vessel vasculitides.

…, C Grasselli, E Chierici, U Maggiore, G Garini… - The Journal of …, 2006 - jrheum.org
OBJECTIVE: To identify the prognostic factors of relapse and/or death during the course of
primary small-vessel vasculitides (PSVV), and to differentiate their prognostic relevance by …

Apparent preferential loss of heterozygosity at TSC2 over TSC1 chromosomal region in tuberous sclerosis hamartomas

…, P Falzoni, G Monga, G Garini… - Genes …, 1996 - Wiley Online Library
To investigate the molecular mechanisms of tuberous sclerosis (TSC) histopathologic lesions,
we have tested for loss of heterozygosity the two TSC loci (TSC1 and TSC2) and seven …

Critical appraisal of haemofiltration and ultra-filtration. The development of ultra-short dialysis: preliminary results

V Cambi, L Arisi, L Bignardi, G Garini, E Rossi… - Journal of …, 1978 - Taylor & Francis
The clinical experience obtained with 2 hours every other day recirculation dialysis, using 20-40
liters of dialysate, without sorbents, and standard cuprophane dialyzers of 1.0-1.5 sq.mt. …

Treatment of AL amyloidosis with 4′-iodo-4′-deoxydoxorubicin: an update

…, MJ Lechuga, G Capri, L Gianni - Blood, The Journal …, 1999 - ashpublications.org
Amyloidosis formed by monoclonal immunoglobulin light chain (AL) is a rapidly progressive
disease in most patients, causing organ failure and death within 1 to 3 years of diagnosis. 1, …

Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis.

…, I Zorzoli, MG Marinone, P Garini - Proceedings of the …, 1995 - National Acad Sciences
All types of amyloidosis are structurally characterized by the cross beta-pleated sheet
conformation of the fibrils, irrespective of their biochemical composition. The clinical observation …

Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria

P Ruggenenti, A Perna, G Gherardi, G Garini, C Zoccali… - The Lancet, 1999 - thelancet.com
… We thank Gianni Tognoni for his constructive comments. This study was supported by a
grant from Hoechst Mario Roussel Clinical Research Institute, Frankfurt am Main, Germany. …

New drug therapy of amyloidoses: resorption of AL-type deposits with 4'-iodo-4'-deoxydoxorubicin

L Gianni, V Bellotti, AM Gianni, G Merlini - 1995 - ashpublications.org
Amyloidosis caused by monoclonal Ig light chains (AL) is characterized by the tissue
deposition of paraproteins as insoluble fibrils that leads to organ dysfunction and death. After …

Aprotinin 99mTc Myocardial Scan: Risk Stratification of Cardiac Events in Patients with Al/Attr Amyloidosis

…, G Calsamiglia, E Anesi, P Garini - Radioactive Isotopes in …, 1999 - Springer
Myocardial scan with 99m Tc Aprotinin was performed in 89 pts with primary amyloidosis.
Negative results allowed to rule out myocardial involvement in pts with a pre-test probability of …

Long-term results of a risk-adapted approach to melphalan conditioning in autologous peripheral blood stem cell transplantation for primary (AL) amyloidosis

…, L Obici, M Magni, L Brunetti, AM Gianni… - …, 2006 - haematologica.org
BACKGROUND AND OBJECTIVES: High-dose melphalan with autologous peripheral blood
stem cell transplantation (ASCT) is an effective treatment for systemic primary amyloidosis. …

Cells with clonal light chains are present in peripheral blood at diagnosis and in apheretic stem cell harvests of primary amyloidosis

…, S Casarini, P Matteucci, AM Gianni… - Bone marrow …, 1999 - nature.com
In primary systemic amyloidosis, small numbers of bone marrow plasma cells secrete monoclonal
light chains that form extracellular fibrils (amyloid) in various organs. Evidence limited …