The classification of glomerulonephritis in systemic lupus erythematosus revisited.The currently
used classification reflects our understanding of the pathogenesis of the various forms of …

Background Since anecdotal series and small, prospective, controlled trials suggest that
mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are desirable. …

Recent studies have suggested that mycophenolate mofetil (MMF) may offer advantages
over intravenous cyclophosphamide (IVC) for the treatment of lupus nephritis, but these …

Objective To evaluate the efficacy and safety of rituximab in a randomized, double‐blind,
placebo‐controlled phase III trial in patients with lupus nephritis treated concomitantly with …

Background Maintenance therapy, often with azathioprine or mycophenolate mofetil, is
required to consolidate remission and prevent relapse after the initial control of lupus nephritis. …

C3 glomerulopathy is a recently introduced pathological entity whose original definition was
glomerular pathology characterized by C3 accumulation with absent or scanty …

In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement
plays a primary role in disease pathogenesis. Herein we report the outcome of a 2015 …

Background/Aims: Pimagedine inhibits the formation of advanced glycation end products
and slows the progression of diabetic complications in experimental models. This study was …

Background Exome sequencing is emerging as a first-line diagnostic method in some clinical
disciplines, but its usefulness has yet to be examined for most constitutional disorders in …

Abstract. Collapsing focal segmental glomerulosclerosis (FSGS) is a distinct clinicopathologic
entity seen most commonly in young African American patients who present with renal …