User profiles for Genny del Zotto
Genny Del ZottoIstituto G. Gaslini Verified email at gaslini.org Cited by 4135 |
Human NK cells: surface receptors, inhibitory checkpoints, and translational applications
NK cells play important roles in innate defenses against viruses and in the control of tumor
growth and metastasis. The regulation/induction of NK cell function is mediated by an array of …
growth and metastasis. The regulation/induction of NK cell function is mediated by an array of …
[HTML][HTML] Killer Ig-like receptors (KIRs): their role in NK cell modulation and developments leading to their clinical exploitation
Natural killer (NK) cells contribute to the first line of defense against viruses and to the control
of tumor growth and metastasis spread. The discovery of HLA class I specific inhibitory …
of tumor growth and metastasis spread. The discovery of HLA class I specific inhibitory …
Human NK cell receptors/markers: a tool to analyze NK cell development, subsets and function
Natural killer (NK) cells are important components of the innate immunity and play a key role
in host defense by virtue of their ability to release cytokines and to mediate cytolytic activity …
in host defense by virtue of their ability to release cytokines and to mediate cytolytic activity …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
…, D Davies, S De Biasi, G Del Zotto… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical aspects of …
immunology and flow cytometry community. They provide the theory and key practical aspects of …
Guidelines for the use of flow cytometry and cell sorting in immunological studies*
…, D Davies, S De Biasi, G Del Zotto… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of detecting
photons of different wavelengths over a high dynamic range. In order to achieve a high …
photons of different wavelengths over a high dynamic range. In order to achieve a high …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
…, S De Biasi, G De Simone, G Del Zotto… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …
performing flow cytometry experiments and includes comprehensive sections describing …
[HTML][HTML] PD/1-PD-Ls checkpoint: insight on the potential role of NK cells
The identification of inhibitory NK cell receptors specific for HLA-I molecules (KIRs and
NKG2A) provided the molecular basis for clarifying the mechanism by which NK cells kill …
NKG2A) provided the molecular basis for clarifying the mechanism by which NK cells kill …
Human natural killer cells: origin, receptors, function, and clinical applications
Natural killer (NK) cells are important effectors playing a relevant role in innate immunity,
primarily in tumor surveillance and in defenses against viruses. Human NK cells recognize HLA …
primarily in tumor surveillance and in defenses against viruses. Human NK cells recognize HLA …
[PDF][PDF] Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
A cardinal feature of COVID-19 is lung inflammation and respiratory failure. In a prospective
multi-country cohort of COVID-19 patients, we found that increased Notch4 expression on …
multi-country cohort of COVID-19 patients, we found that increased Notch4 expression on …
Markers and function of human NK cells in normal and pathological conditions
Natural killer (NK) cells, the most important effectors of the innate lymphoid cells (ILCs), play
a fundamental role in tumor immune‐surveillance, defense against viruses and, in general, …
a fundamental role in tumor immune‐surveillance, defense against viruses and, in general, …