Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats
GR Norton, G Candy, AJ Woodiwiss - Circulation, 1996 - Am Heart Assoc
Background A decreased cardiac compliance is a major feature of the cardiomyopathy of
diabetes mellitus. Either an increase in the resistance afterload to the LV or an increase in …
diabetes mellitus. Either an increase in the resistance afterload to the LV or an increase in …
Cross-linking influences the impact of quantitative changes in myocardial collagen on cardiac stiffness and remodelling in hypertension in rats
…, A Naidoo, R Brooksbank, GR Norton… - Cardiovascular …, 2003 - academic.oup.com
Objective: To assess whether the variable impact of quantitative changes in myocardial
collagen on left ventricular (LV) diastolic myocardial stiffness (myocardial k) and remodelling (…
collagen on left ventricular (LV) diastolic myocardial stiffness (myocardial k) and remodelling (…
Heart failure in pressure overload hypertrophy: The relative roles of ventricularremodeling and myocardial dysfunction
GR Norton, AJ Woodiwiss, WH Gaasch, T Mela… - Journal of the American …, 2002 - jacc.org
Objectives : We sought to explore the relative contributions of ventricular remodeling and
myocardial dysfunction to heart failure in pressure overload hypertrophy (POH). Background : …
myocardial dysfunction to heart failure in pressure overload hypertrophy (POH). Background : …
Obesity promotes left ventricular concentric rather than eccentric geometric remodeling and hypertrophy independent of blood pressure
…, E Libhaber, M Maseko, GR Norton - American journal of …, 2008 - academic.oup.com
Background As it is uncertain whether excess adiposity promotes primarily concentric or
eccentric left ventricular hypertrophy (LVH), we aimed to determine at a population level, the …
eccentric left ventricular hypertrophy (LVH), we aimed to determine at a population level, the …
Ethnic differences in arterial wave reflections and normative equations for augmentation index
…, J Medina-Lezama, Y Li, AJ Woodiwiss, GR Norton… - …, 2011 - Am Heart Assoc
Data regarding ethnic differences in wave reflections, which markedly affect the central
pressure profile, are very limited. Furthermore, because age, heart rate, and body height are …
pressure profile, are very limited. Furthermore, because age, heart rate, and body height are …
Nurse-recorded auscultatory blood pressure at a single visit predicts target organ changes as well as ambulatory blood pressure
…, R Brooksbank, P Sareli, GR Norton - Journal of …, 2009 - journals.lww.com
Aim To determine whether high-quality nurse-recorded auscultatory blood pressure (BP)
values obtained at a single visit predict cardiovascular target organ changes as closely as …
values obtained at a single visit predict cardiovascular target organ changes as closely as …
Relationship between urinary salt excretion and pulse pressure and central aortic hemodynamics independent of steady state pressure in the general population
…, GR Norton, L Scott, MJ Maseko, R Brooksbank… - …, 2010 - Am Heart Assoc
Although central pulse pressure (PPc) is strongly related to central mean arterial pressure (MAPc),
PPc predicts cardiovascular outcomes beyond MAPc. Whether modifiable risk factors …
PPc predicts cardiovascular outcomes beyond MAPc. Whether modifiable risk factors …
Reference values for SphygmoCor measurements in South Africans of African ancestry
…, AJ Woodiwiss, GR Norton - American journal of …, 2006 - academic.oup.com
Background: Measurements of blood pressure (BP) together with applanation tonometry at
the radial and femoral arteries allow for reproducible assessments of various indexes of …
the radial and femoral arteries allow for reproducible assessments of various indexes of …
Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritis.
PH Dessein, GR Norton, AJ Woodiwiss… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: To determine whether nontraditional risk factors increase the accuracy of
predicting the presence of carotid artery plaque based on traditional cardiovascular risk factors …
predicting the presence of carotid artery plaque based on traditional cardiovascular risk factors …
Obesity and left ventricular hypertrophy: the hypertension connection
AJ Woodiwiss, GR Norton - Current hypertension reports, 2015 - Springer
The detection of left ventricular hypertrophy (LVH) is recommended for risk prediction, and
changes in LV geometry may provide further prognostic information. Obesity is a major …
changes in LV geometry may provide further prognostic information. Obesity is a major …