Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats

GR Norton, G Candy, AJ Woodiwiss - Circulation, 1996 - Am Heart Assoc
Background A decreased cardiac compliance is a major feature of the cardiomyopathy of
diabetes mellitus. Either an increase in the resistance afterload to the LV or an increase in …

Cross-linking influences the impact of quantitative changes in myocardial collagen on cardiac stiffness and remodelling in hypertension in rats

…, A Naidoo, R Brooksbank, GR Norton… - Cardiovascular …, 2003 - academic.oup.com
Objective: To assess whether the variable impact of quantitative changes in myocardial
collagen on left ventricular (LV) diastolic myocardial stiffness (myocardial k) and remodelling (…

Heart failure in pressure overload hypertrophy: The relative roles of ventricularremodeling and myocardial dysfunction

GR Norton, AJ Woodiwiss, WH Gaasch, T Mela… - Journal of the American …, 2002 - jacc.org
Objectives : We sought to explore the relative contributions of ventricular remodeling and
myocardial dysfunction to heart failure in pressure overload hypertrophy (POH). Background : …

Obesity promotes left ventricular concentric rather than eccentric geometric remodeling and hypertrophy independent of blood pressure

…, E Libhaber, M Maseko, GR Norton - American journal of …, 2008 - academic.oup.com
Background As it is uncertain whether excess adiposity promotes primarily concentric or
eccentric left ventricular hypertrophy (LVH), we aimed to determine at a population level, the …

Ethnic differences in arterial wave reflections and normative equations for augmentation index

…, J Medina-Lezama, Y Li, AJ Woodiwiss, GR Norton… - …, 2011 - Am Heart Assoc
Data regarding ethnic differences in wave reflections, which markedly affect the central
pressure profile, are very limited. Furthermore, because age, heart rate, and body height are …

Nurse-recorded auscultatory blood pressure at a single visit predicts target organ changes as well as ambulatory blood pressure

…, R Brooksbank, P Sareli, GR Norton - Journal of …, 2009 - journals.lww.com
Aim To determine whether high-quality nurse-recorded auscultatory blood pressure (BP)
values obtained at a single visit predict cardiovascular target organ changes as closely as …

Relationship between urinary salt excretion and pulse pressure and central aortic hemodynamics independent of steady state pressure in the general population

…, GR Norton, L Scott, MJ Maseko, R Brooksbank… - …, 2010 - Am Heart Assoc
Although central pulse pressure (PPc) is strongly related to central mean arterial pressure (MAPc),
PPc predicts cardiovascular outcomes beyond MAPc. Whether modifiable risk factors …

Reference values for SphygmoCor measurements in South Africans of African ancestry

…, AJ Woodiwiss, GR Norton - American journal of …, 2006 - academic.oup.com
Background: Measurements of blood pressure (BP) together with applanation tonometry at
the radial and femoral arteries allow for reproducible assessments of various indexes of …

Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritis.

PH Dessein, GR Norton, AJ Woodiwiss… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: To determine whether nontraditional risk factors increase the accuracy of
predicting the presence of carotid artery plaque based on traditional cardiovascular risk factors …

Obesity and left ventricular hypertrophy: the hypertension connection

AJ Woodiwiss, GR Norton - Current hypertension reports, 2015 - Springer
The detection of left ventricular hypertrophy (LVH) is recommended for risk prediction, and
changes in LV geometry may provide further prognostic information. Obesity is a major …