Objective The assessment of health-related quality-of-life (HRQoL) in rheumatoid arthritis (RA)
is becoming increasingly common in both research and clinical practice. One of the most …

Objective. MTX is widely used to treat synovitis in PsA without supporting trial evidence. The
aim of our study was to test the value of MTX in the first large randomized placebo-…

Objective. We evaluated fibromyalgic RA to determine its clinical impact, identification using
core clinical assessments and influence identifying active disease using disease activity …

The value of epidural injections of corticosteroid as an outpatient treatment of sciatica has
been hitherto uncertain. An epidural injection of 80 mg methylprednisolone in 10 ml …

There are large differences in the antigenicity and biology of the ReA-associated bacteria.
For induction of arthritis, the relevance seems to be only that antigenic material reaches the …

Objective. We examined how combination DMARD therapies and TNF inhibitors therapies
plus MTX (TNF/MTX) affect clinical and radiological outcomes compared with MTX …

Objective. Calprotectin (myeloid-related protein 8/14), a heterodimeric complex of calcium-binding
proteins, is expressed in granulocytes and monocytes. Calprotectin levels are high in …

Aims: To determine the risks of cardiac failure with non‐steroidal anti‐inflammatory drugs (NSAIDs)
and the specific risks with Cox‐2 specific NSAIDs (COXIBs). Methods: We performed …

Objective. We systematically reviewed remission as an outcome measure in observational
studies and randomized controlled trials (RCT) in early rheumatoid arthritis (RA). Our …

Objective To determine whether intensive combinations of synthetic disease modifying drugs
can achieve similar clinical benefits at lower costs to high cost biologics such as tumour …