Objective Non-alcoholic fatty liver disease (NAFLD) is prevalent among obese people and
is considered the hepatic manifestation of metabolic syndrome. However, not all obese …

Liver steatosis, which involves accumulation of intracytoplasmic lipid droplets, is characteristic
of hepatitis C virus (HCV) infection. By use of an in vivo transgenic murine model, we …

Background Intestinal microbiota plays an important role in bile acid homeostasis. Aim To
study the structure of the intestinal microbiota and its function in bile acid homeostasis in …

Objective Antidepressant drugs can cause drug-induced liver injury (DILI). The authors review
clinical data relevant to antidepressant-induced liver injury and provide recommendations …

The majority of infectious hepatitis C particles are present in the low-density fractions from
plasma of infected patients, suggesting an association of the virus with lipoproteins and the …

Recent advances in the understanding of molecular mechanisms of cancer have led to the
development of novel compounds that target specific cancer pathways. These drugs …

Nonalcoholic steatohepatitis (NASH) may progress to liver fibrosis and cirrhosis. Mechanisms
directly involved in the development of fibrosis have been poorly investigated. Because …

Objective Alcoholic liver disease (ALD) is a global health problem with limited therapeutic
options. Intestinal barrier integrity and the microbiota modulate susceptibility to ALD. …

FibroTest has been validated as a biomarker of fibrosis in patients with chronic viral hepatitis,
with a similar prognostic value as biopsy. The aim of the study was to compare the …

Background & Aims Alcoholic liver disease (ALD) is a leading cause of liver failure and
mortality. In humans, severe alcoholic hepatitis is associated with key changes to intestinal …