… Graciela S Alarcón20, … the use of a validated index which could be supplemented with
a physician’s global assessment (PGA). Additionally, two categories of remission should be …

Aim A decrease in proteinuria has been considered protective from renal damage in lupus
nephritis (LN), but a cut-off point has yet to be established. The aim of this study was to …

… This approach was applied by the SLICC subcommittee (chaired by Graciela S. Alarcón,
MD, MPH), using the candidate set of variables to result in a preliminary data-driven …

… Current investigators and staff in the LUMINA (LUpus in MInorities, NAture versus nurture)
study are as follows: Graciela S. Alarcón, MD, MPH, Holly M. Bastian, MD, MSPH, Barri J. …

OBJECTIVES: This review examines the burden and patterns of disease in systemic lupus
erythematosus (SLE) and the influence and interactions of gender, ethnicity, age, and …

Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …

Objective. To develop a standardized nomenclature system for the neuropsychiatric syndromes
of systemic lupus erythematosus (NPSLE). Methods. An international, multidisciplinary …

Increased levels of B lymphocyte stimulator (BLyS) are associated with systemic
autoimmunity in animal models of spontaneous autoimmune disease, and transgenic animals …

Background: There is concern that exogenous female hormones may worsen disease activity
in women with systemic lupus erythematosus (SLE). Objective: To evaluate the effect of …

Methotrexate (MTX) has become an important drug in the treatment of rheumatoid arthritis (RA).
The American College of Rheumatology convened a committee to assess the risks of …