User profiles for GERJAN J. NAVIS

Gerjan Navis

Internist, professor of Nutrition in Medicine
Verified email at umcg.nl
Cited by 61988

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

…, W Timens, JL Hillebrands, GJ Navis… - The Journal of …, 2020 - Wiley Online Library
Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional host
receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

Comparative performance of the CKD Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD) Study equations for estimating …

…, GJ Navis, MW Steffes, PW Eggers, J Coresh… - American Journal of …, 2010 - Elsevier
BACKGROUND: The Modification of Diet in Renal Disease (MDRD) Study equation
underestimates measured glomerular filtration rate (GFR) at levels >60 mL/min/1.73 m 2 , with …

[HTML][HTML] Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

…, F Ernst, F Kronenberg, FB Hu, GJ Navis… - Nature …, 2016 - nature.com
Reduced glomerular filtration rate defines chronic kidney disease and is associated with
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …

[HTML][HTML] Moderation of dietary sodium potentiates the renal and cardiovascular protective effects of angiotensin receptor blockers

HJL Heerspink, FA Holtkamp, HH Parving, GJ Navis… - Kidney international, 2012 - Elsevier
Dietary sodium restriction has been shown to enhance the short-term response of blood
pressure and albuminuria to angiotensin receptor blockers (ARBs). Whether this also enhances …

[HTML][HTML] Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy

…, H Sourij, B Tiran, BM Winklhofer-Roob, GJ Navis… - PloS one, 2010 - journals.plos.org
Background Urine proteome analysis is rapidly emerging as a tool for diagnosis and prognosis
in disease states. For diagnosis of diabetic nephropathy (DN), urinary proteome analysis …

Secretory Phospholipase A2-IIA and Cardiovascular Disease: A Mendelian Randomization Study

…, LM Holdt, F Beutner, RT Gansevoort, GJ Navis… - Journal of the American …, 2013 - jacc.org
Objectives : This study sought to investigate the role of secretory phospholipase A 2 (sPLA 2
)-IIA in cardiovascular disease. Background : Higher circulating levels of sPLA 2 -IIA mass …

A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy

…, GS Mijnhout, HJG Bilo, ROB Gans, GJ Navis… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE To investigate the effect of benfotiamine on urinary albumin excretion (UAE)
and the tubular damage marker kidney injury molecule-1 (KIM-1) in patients with type 2 …

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

…, GH Tofler, A Silveira, GJ Navis… - Blood, The Journal …, 2012 - ashpublications.org
We conducted a genome-wide association study to identify novel associations between
genetic variants and circulating plasminogen activator inhibitor-1 (PAI-1) concentration, and …

[HTML][HTML] Low potassium excretion but not high sodium excretion is associated with increased risk of developing chronic kidney disease

LM Kieneker, SJL Bakker, RA de Boer, GJ Navis… - Kidney international, 2016 - Elsevier
It is unclear whether sodium and potassium intake is relevant to the development of chronic
kidney disease (CKD) in the general population. Our aim was to examine the associations of …

[HTML][HTML] Ultraprocessed food consumption and kidney function decline in a population-based cohort in the Netherlands

…, SJL Bakker, MH de Borst, GJ Navis - The American journal of …, 2022 - Elsevier
Background Ultraprocessing makes food products more convenient, appealing, and
profitable. Recent studies show that high ultraprocessed food (UPF) intake is associated with …