MET and its ligand HGF are involved in many biological processes, both physiological and
pathological, making this signaling pathway an attractive therapeutic target in oncology. …

Pancreatic ductal adenocarcinoma is the fourth cause of death in the Western world.
Surgery remains the only treatment offering an advantage in terms of overall survival (5-year …

Nowadays molecular biology represents one of the most interesting topics in medical
oncology, because it provides a global and detailed view on the molecular changes involved in …

Objectives. This study was performed to evaluate the effects of l-carnitine administration on
long-term left ventricular dilation in patients with acute anterior myocardial infarction. …

… Cell lysates were incubated 1 h on ice and centrifuged at 12 000 g to collect supernatants.
After addition of SDS-PAGE sample buffer and boiling, 40 μg of denatured proteins were …

Background: Using the ‘surprise’ question ‘Would you be surprised if this patient died in the
next year?’ may improve physicians’ prognostic accuracy and identify people appropriate for …

Patients treated with platinum compounds are subject to hypersensitivity reactions. Our study
has highlighted the reactions related to oxaliplatin (OHP) infusion. One hundred and twenty…

… Massively parallel sequencing analysis revealed that GIST_07 had a C to G transversion
at nucleotide 1151 in exon 9 of SDHA , a nonsense mutation resulting in the replacement of …

BACKGROUND The objectives of this study were to provide sunitinib to patients with
gastrointestinal stromal tumor (GIST) who were otherwise unable to obtain it and to collect broad …

Background Although the feasibility of laparoscopic resection of gastric gastrointestinal stromal
tumors (GISTs) has been established, various aspects are debated. This paper describes …