The diagnosis of rheumatoid arthritis (RA) is primarily based on clinical symptoms, so it is
often difficult to diagnose RA in very early stages of the disease. A disease-specific …

PURPOSE: Studies on mortality associated with systemic sclerosis have been limited by
small sample sizes. We aimed to obtain large-scale evidence on survival outcomes and …

Systemic sclerosis (SSc) is a severe auto-immune disease, characterized by vasculopathy
and fibrosis of connective tissues. SSc has a high morbidity and mortality and unfortunately …

… Frank van den Hoogen … Van den Hoogen and Pope had full access to all of the data in the
study and take responsibility for the integrity of the data and the accuracy of the data analysis. …

Objective Since modern treatment of rheumatoid arthritis (RA) is shifting toward aggressive
antirheumatic therapy in an early phase of the disease, diagnostic tests with high specificity …

The prognostic value of antiâ•ficyclic citrullinated peptide antibody in patients with recentâ•’onset
rheumatoid arthri Page 1 ARTHRITIS & RHEUMATISM Vol. 43, No. 8, August 2000, pp …

The aim was to update the 2009 European League against Rheumatism (EULAR)
recommendations for the treatment of systemic sclerosis (SSc), with attention to new therapeutic …

Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell
transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …

Background: Tumour necrosis factor α (TNFα) neutralising antibody constructs are
increasingly being used to treat rheumatoid arthritis (RA). Objective: To determine potential …

Identifying mutations that cause specific osteochondrodysplasias will provide novel insights
into the function of genes that are essential for skeletal morphogenesis. We report here that …