User profiles for Francesco Trotta

Francesco Trotta

- Verified email at unito.it - Cited by 12979

Francesco Trotta

- Verified email at aifa.gov.it - Cited by 2528

Cyclodextrin-based nanosponges encapsulating camptothecin: Physicochemical characterization, stability and cytotoxicity

…, L Serpe, F Trotta, P Vavia, D Aquilano, M Trotta… - European journal of …, 2010 - Elsevier
Camptothecin (CAM), a plant alkaloid and a potent antitumor agent, has a limited therapeutic
utility because of its poor aqueous solubility, lactone ring instability and serious side effects…

Thermal degradation of cyclodextrins

F Trotta, M Zanetti, G Camino - Polymer degradation and Stability, 2000 - Elsevier
The thermal degradation of cyclodextrins and substituted β-cyclodextrins has been studied. It
is found that in inert atmosphere they all decompose in one major step (252–400C) leaving …

Cyclodextrin-Based Nanosponges for Delivery of Resveratrol: In Vitro Characterisation, Stability, Cytotoxicity and Permeation Study

KA Ansari, PR Vavia, F Trotta, R Cavalli - Aaps Pharmscitech, 2011 - Springer
The aim of this work was to increase the solubility, stability and permeation of resveratrol by
complexation with cyclodextrin-based nanosponges (NS). Nanosponges are recently …

[HTML][HTML] Cyclodextrin-based nanosponges as drug carriers

F Trotta, M Zanetti, R Cavalli - Beilstein journal of organic …, 2012 - beilstein-journals.org
Cyclodextrin-based nanosponges, which are proposed as a new nanosized delivery system,
are innovative cross-linked cyclodextrin polymers nanostructured within a three-…

Encapsulation of Acyclovir in new carboxylated cyclodextrin-based nanosponges improves the agent's antiviral efficacy

…, L Pastero, D Aquilano, P Vavia, F Trotta… - International journal of …, 2013 - Elsevier
Cyclodextrin-based nanosponges (NS) are solid nanoparticles, obtained from the cross-linking
of cyclodextrins that have been proposed as delivery systems for many types of drugs. …

Cyclodextrin-based nanosponges: effective nanocarrier for Tamoxifen delivery

S Torne, S Darandale, P Vavia, F Trotta… - Pharmaceutical …, 2013 - Taylor & Francis
The purpose of the present study was to develop Tamoxifen loaded β-cyclodextrin nanosponges
for oral drug delivery. The three types of Tamoxifen loaded β-cyclodextrin nanosponges …

Nanosponge formulations as oxygen delivery systems

…, AK Akhter, A Bisazza, P Giustetto, F Trotta… - International journal of …, 2010 - Elsevier
Three types of cyclodextrin nanosponges were synthetized cross-linking α, β or γ cyclodextrin
with carbonyldiimidazole as cross-linker. Nanosponges are solid nanoparticles previously …

[HTML][HTML] History of cyclodextrin nanosponges

…, A Rubin Pedrazzo, C Cecone, R Cavalli, F Trotta - Polymers, 2020 - mdpi.com
Nowadays, research in the field of nanotechnology and nanomedicine has become
increasingly predominant, focusing on the manipulation and development of materials on a …

Cyclodextrin-based nanosponges for drug delivery

R Cavalli, F Trotta, W Tumiatti - Journal of inclusion phenomena and …, 2006 - Springer
Nanosponges were prepared from β-cyclodextrins as nanoporous materials for possible
use as carriers for drug delivery. The structure of β-cyclodextrin-based nanosponges was …

The incidence of narcolepsy in Europe: before, during, and after the influenza A (H1N1) pdm09 pandemic and vaccination campaigns

…, N van der Maas, M Partinen, S Romio, F Trotta… - Vaccine, 2013 - Elsevier
BACKGROUND: In August 2010 reports of a possible association between exposure to AS03
adjuvanted pandemic A(H1N1)pdm09 vaccine and occurrence of narcolepsy in children …