Infections remain the leading cause of death after major burns. Trace elements are involved
in immunity and burn patients suffer acute trace element depletion after injury. In a previous …

Objectives Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disease;
its management is largely empirical. This is the first clinical study to determine if interleukin (IL)…

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several
factors, including age, prominent symptoms, symptom severity, control of AR, patient …

Background The ongoing Ebola outbreak led to accelerated efforts to test vaccine candidates.
On the basis of a request by WHO, we aimed to assess the safety and immunogenicity of …

Background Plasmodium falciparum merozoite surface protein 3 is a malaria vaccine
candidate that was identified, characterised, and developed based on a unique immuno-clinical …

Objective We developed interferon‐α–kinoid (IFN‐K), a drug composed of inactivated IFNα
coupled to a carrier protein, keyhole limpet hemocyanin. In human IFNα–transgenic mice, IFN…

Background Tuberculosis remains one of the world's deadliest transmissible diseases despite
widespread use of the BCG vaccine. MTBVAC is a new live tuberculosis vaccine based …

The C-terminal conserved region of Plasmodium falciparum merozoite surface protein 3 (MSP3)
is the trigger antigen of a protective immune response mediated by cytophilic antibodies…

In addition to being instrumental to the protection of mucosal epithelia, secretory IgA (SIgA)
adheres to and is transported by intestinal Peyer’s patch (PP) M cells. The possible functional …

Biologic agents have substantially advanced the treatment of immunological disorders,
including chronic inflammatory and autoimmune diseases. However, these drugs are often …