Aims/hypothesis The Di@bet.es Study is the first national study in Spain to examine the
prevalence of diabetes and impaired glucose regulation. Methods A population-based, cross-…

Background A recent study using a rat model found significant differences at the time of
diabetes onset in the bacterial communities responsible for type 1 diabetes modulation. We …

Background: Prospective longitudinal studies evaluating the relevance of “Metabolically
Healthy but Obese” (MHO) phenotype at risk for type 2 diabetes mellitus (T2D) and …

Context: The association between thyroid function during pregnancy and the later mental
and psychomotor development of the child is supported by numerous experimental, clinical, …

Background The physiological role of apelin in obesity and diabetes remains unclear.
Although apelin has been studied in persons with different conditions, no studies have yet …

Background The family kitchen resembles an uncontrolled laboratory experiment, and some
discrepancies in the relation between the risk of hypertension and dietary fat may be partly …

Type 2 diabetes has been catalogued as the epidemic of the 21st Century, both because of
its increasing magnitude and its impact on cardiovascular disease, the leading cause of …

Glucokinase (GK) is a glycolytic key enzyme that functions as a glucose sensor in the
pancreatic β-cell, where it governs glucose-stimulated insulin secretion (GSIS). Heterozygous …

The association between iodine deficiency and poor mental and psychomotor development
is known. However, most studies were undertaken in areas of very low iodine intake. We …

Background: Vitamin D deficiency is common worldwide. No homogenous reference values
have yet been established and no studies of values have been conducted in Spain involving …