User profiles for FRANZ JAKOB
Franz JakobHead of Orthopedic Center for Musculoskeletal Research, Chair of Musculoskeletal Center … Verified email at uni-wuerzburg.de Cited by 13467 |
How smart do biomaterials need to be? A translational science and clinical point of view
Over the last 4 decades innovations in biomaterials and medical technology have had a
sustainable impact on the development of biopolymers, titanium/stainless steel and ceramics …
sustainable impact on the development of biopolymers, titanium/stainless steel and ceramics …
Effect of ozone on oral cells compared with established antimicrobials
KC Huth, FM Jakob, B Saugel… - European journal of …, 2006 - Wiley Online Library
Ozone has been proposed as an alternative antiseptic agent in dentistry based on reports of
its antimicrobial effects in both gaseous and aqueous forms. This study investigated …
its antimicrobial effects in both gaseous and aqueous forms. This study investigated …
Additive manufacturing of scaffolds with sub-micron filaments via melt electrospinning writing
The aim of this study was to explore the lower resolution limits of an electrohydrodynamic
process combined with direct writing technology of polymer melts. Termed melt electrospinning …
process combined with direct writing technology of polymer melts. Termed melt electrospinning …
Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite of …
Human bone marrow mesenchymal stem cells (hMSC) represent a population of stem cells
that are capable of differentiation into multiple lineages. However, these cells exhibit …
that are capable of differentiation into multiple lineages. However, these cells exhibit …
Chondrogenic differentiation of human mesenchymal stem cells in collagen type I hydrogels
…, A Steinert, N Schütze, F Jakob… - … Research Part A: An …, 2007 - Wiley Online Library
The chondrogenic differentiation of bone marrow‐derived human mesenchymal stem cells (MSCs)
in a collagen type I hydrogel, which is in clinical use for matrix‐based autologous …
in a collagen type I hydrogel, which is in clinical use for matrix‐based autologous …
[HTML][HTML] Selected Novel Flavones Inhibit the DNA Binding or the DNA Religation Step of Eukaryotic Topoisomerase I (∗)
…, K Christiansen, A Andersen, F Jakob… - Journal of Biological …, 1996 - ASBMB
Topoisomerases are involved in many aspects of DNA metabolism such as replication and
transcription reactions. Camptothecins, which stabilize the covalent intermediate of …
transcription reactions. Camptothecins, which stabilize the covalent intermediate of …
Effects of high glucose on mesenchymal stem cell proliferation and differentiation
High glucose (HG) concentrations impair cellular functions and induce apoptosis. Exposition
of mesenchymal stem cells (MSC) to HG was reported to reduce colony forming activity and …
of mesenchymal stem cells (MSC) to HG was reported to reduce colony forming activity and …
Novel approaches to target the microenvironment of bone metastasis
Bone metastases are a frequent and severe complication of advanced-stage cancers. Breast
and prostate cancers, the most common malignancies in women and men, respectively, …
and prostate cancers, the most common malignancies in women and men, respectively, …
[HTML][HTML] The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors
…, S Zeck, T Schinke, M Amling, R Ebert, F Jakob - 2012 - journals.plos.org
Primary osteoporosis is an age-related disease characterized by an imbalance in bone
homeostasis. While the resorptive aspect of the disease has been studied intensely, less is …
homeostasis. While the resorptive aspect of the disease has been studied intensely, less is …
Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stromal cells in vitro
Bone marrow stromal cells (BMSCs) and other cell populations derived from mesenchymal
precursors are developed for cell‐based therapeutic strategies and undergo cellular stress …
precursors are developed for cell‐based therapeutic strategies and undergo cellular stress …