Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus …

E Traggiai, S Volpi, F Schena, M Gattorno, F Ferlito… - Stem …, 2008 - academic.oup.com
Human bone marrow multipotent mesenchymal stromal cells are progenitor cells that can be
expanded in vitro and differentiate into various cells of mesodermal origin. They contribute …

The pattern of response to anti–interleukin‐1 treatment distinguishes two subsets of patients with systemic‐onset juvenile idiopathic arthritis

…, G Brisca, S Carta, L Delfino, F Ferlito… - Arthritis & …, 2008 - Wiley Online Library
Objective To assess the clinical response to interleukin‐1 (IL‐1) blockade and in vitro IL‐1β
and IL‐18 secretion in patients with systemic‐onset juvenile idiopathic arthritis (JIA). …

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

CR Ruprecht, M Gattorno, F Ferlito… - The Journal of …, 2005 - rupress.org
A better understanding of the role of CD4 + CD25 + regulatory T cells in disease pathogenesis
should follow from the discovery of reliable markers capable of discriminating regulatory …

Pattern of interleukin‐1β secretion in response to lipopolysaccharide and ATP before and after interleukin‐1 blockade in patients with CIAS1 mutations

…, S Tassi, S Carta, L Delfino, F Ferlito… - … : Official Journal of …, 2007 - Wiley Online Library
Objective To examine the synthesis, processing, and secretion of interleukin‐1β (IL‐1β), as
well as the clinical and biologic effects of IL‐1 blockade, in patients with chronic infantile …

CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells

…, I Pierri, A Bolognesi, F Ferlito… - Blood, The Journal …, 2003 - ashpublications.org
The expression of cytotoxic T-lymphocyte antigen–4 (CTLA-4) molecule in human normal
and neoplastic hematopoietic cells, both on the cell membrane and in the intracellular …

Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor–induced apoptosis: Pathogenetic and clinical implications

A D'Osualdo, F Ferlito, I Prigione, L Obici… - Arthritis & …, 2006 - Wiley Online Library
Objective To explore tumor necrosis factor (TNF)–induced apoptosis in neutrophils from
patients with TNF receptor–associated periodic syndrome (TRAPS) and to correlate the results …

[HTML][HTML] Phenotypic and functional characterisation of CCR7+ and CCR7- CD4+memory T cells homing to the joints in juvenile idiopathic arthritis

…, I Prigione, F Morandi, A Gregorio, S Chiesa, F Ferlito… - Arthritis Res Ther, 2005 - Springer
The aim of the study was to characterise CCR7 + and CCR7 - memory T cells infiltrating the
inflamed joints of patients with juvenile idiopathic arthritis (JIA) and to investigate the …

[HTML][HTML] Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis

A Corcione, F Ferlito, M Gattorno, A Gregorio… - Arthritis research & …, 2009 - Springer
Introduction In chronic inflammatory disorders, B cells can contribute to tissue damage by
autoantibody production and antigen presentation to T cells. Here, we have characterized …

Single-center experience and preliminary results of intravascular ultrasound in endovascular aneurysm repair

…, UM Bracale, A Farina, G Badalamenti, F Ferlito… - Annals of vascular …, 2019 - Elsevier
Background Intravascular ultrasound (IVUS) has been introduced as diagnostic adjunct to
provide new insights into the diagnosis and therapy of vascular disease. Herein, we …

Hypoxic synovial environment and expression of macrophage inflammatory protein 3γ/CCL20 in juvenile idiopathic arthritis

MC Bosco, S Delfino, F Ferlito… - … : Official Journal of …, 2008 - Wiley Online Library
Objective Synovial inflammation is a major determinant of juvenile idiopathic arthritis (JIA)
pathogenesis and is mediated by local chemokine secretion. Monocytic cells are an important …