Familial aggregation of psoriatic arthritis

…, CT Schentag, JE Brockbank, FJ Pellett… - Annals of the …, 2009 - ard.bmj.com
Objectives: The aim of this study was to determine the recurrence risk of psoriatic arthritis (PsA)
and uncomplicated psoriasis in first-degree relatives (FDRs) of patients with PsA. …

Soluble biomarkers differentiate patients with psoriatic arthritis from those with psoriasis without arthritis

…, RJ Cook, J Edwin, H Shen, FJ Pellett… - …, 2010 - academic.oup.com
Objective. Biomarkers may be helpful in screening patients with psoriasis for PsA. Our purpose
was to identify serum biomarkers for psoriasis and PsA. Methods. Fifty-two patients with …

Human leukocyte antigen alleles and susceptibility to psoriatic arthritis

V Chandran, SB Bull, FJ Pellett, R Ayearst… - Human immunology, 2013 - Elsevier
Objective Our purpose was to determine associations between HLA alleles and psoriatic
arthritis (PsA). Methods 678 PsA cases and 688 healthy controls were analyzed in a case–…

Killer-cell immunoglobulin-like receptor gene polymorphisms and susceptibility to psoriatic arthritis

V Chandran, SB Bull, FJ Pellett, R Ayearst… - …, 2014 - academic.oup.com
Objectives. We conducted a case–control study to determine the association between KIR2D
and KIR3D gene polymorphisms and their interaction with HLA alleles in PsA. Methods. A …

Folate pathway enzyme gene polymorphisms and the efficacy and toxicity of methotrexate in psoriatic arthritis

V Chandran, F Siannis, P Rahman, FJ Pellett… - The Journal of …, 2010 - jrheum.org
Objective. To determine the association between folate pathway gene polymorphisms and
the effectiveness, toxicity, and drug survival of methotrexate (MTX) in psoriatic arthritis (PsA). …

Soluble biomarkers associated with response to treatment with tumor necrosis factor inhibitors in psoriatic arthritis

V Chandran, H Shen, RA Pollock, FJ Pellett… - The Journal of …, 2013 - jrheum.org
Objective. To identify soluble biomarkers associated with response to therapy with tumor
necrosis factor inhibitors (TNFi) in patients with psoriatic arthritis (PsA). Methods. The study was …

Gene expression differences between psoriasis patients with and without inflammatory arthritis

…, K Liang, V Chandran, FJ Pellett… - The Journal of …, 2015 - pubmed.ncbi.nlm.nih.gov
J Invest Dermatol. 2015 Feb;135(2):620-623. doi: 10.1038/jid.2014.414. … 3 , Fawnda J Pellett

Association of SEEK1 and psoriatic arthritis in two distinct Canadian populations

…, F Siannis, VT Farewell, L Peddle, FJ Pellett… - Annals of the …, 2005 - ard.bmj.com
Objective: To examine the relationship between SNP +39604 in SEEK1 and psoriatic
arthritis (PsA) in two distinct Canadian populations. Methods: 103 patients with PsA and 105 …

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis

P Rahman, NM Roslin, FJ Pellett, M Lemire… - Annals of the …, 2011 - ard.bmj.com
Objective Psoriatic arthritis (PsA) has a clear familial predisposition, the major histocompatibility
complex (MHC) region being the strongest genetic locus. The study primary objective …

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

, … Association Genetics Extension Pellett Fawnda J 40 … - Nature …, 2012 - nature.com
To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis
of 3 genome-wide association studies (GWAS) and 2 independent data sets genotyped …