Anti-adalimumab antibodies and adalimumab concentrations in psoriatic arthritis; an association with disease activity at 28 and 52 weeks of follow-up

EH Vogelzang, EL Kneepkens… - Annals of the …, 2014 - ard.bmj.com
Objectives To investigate the relationship between antidrug antibodies (ADA), adalimumab
concentrations and clinical response in patients with psoriatic arthritis (PsA) during 52 weeks …

Immunogenicity, adalimumab levels and clinical response in ankylosing spondylitis patients during 24 weeks of follow-up

EL Kneepkens, JCC Wei, MT Nurmohamed… - Annals of the …, 2015 - ard.bmj.com
Background Immunogenicity influences adalimumab levels and therefore clinical response
in patients with rheumatic diseases. Objectives To study the relationship between clinical …

[HTML][HTML] Medication-related hospital readmissions within 30 days of discharge: prevalence, preventability, type of medication errors and risk factors

…, MJA Janssen, CEH Siegert, EL Kneepkens… - Frontiers in …, 2021 - frontiersin.org
Background: Hospital readmission rates are increasingly used as a measure of healthcare
quality. Medicines are the most common therapeutic intervention but estimating the …

Capillary blood microsampling to determine serum biopharmaceutical concentration: Mitra® microsampler vs dried blood spot

K Bloem, T Schaap, R Boshuizen, EL Kneepkens… - Bioanalysis, 2018 - Future Science
Aim: For assessment of concentrations of biopharmaceuticals, for example, therapeutic drug
monitoring, dried blood sampling of capillary blood is a convenient alternative to traditional …

[HTML][HTML] Preventability of unplanned readmissions within 30 days of discharge. A cross-sectional, single-center study

…, EL Kneepkens, EB Uitvlugt, SL Jansen, L Schilder… - PLoS one, 2020 - journals.plos.org
Objectives To identify the preventability, determinants and causes of unplanned hospital
readmissions within 30 days of discharge using a multidisciplinary approach and including …

Golimumab trough levels, antidrug antibodies and clinical response in patients with rheumatoid arthritis treated in daily clinical practice

EL Kneepkens, C Plasencia, CLM Krieckaert… - Annals of the …, 2014 - ard.bmj.com
Tumour necrosis factor inhibitors (TNFi) are effective in the majority of patients with rheumatoid
arthritis (RA), 1 however, an important reason for non-response is low drug level due to …

Dried blood spots from finger prick facilitate therapeutic drug monitoring of adalimumab and anti‐adalimumab in patients with inflammatory diseases

EL Kneepkens, MF Pouw, GJ Wolbink… - British journal of …, 2017 - Wiley Online Library
Aims Development of a self‐sampling method for therapeutic drug monitoring (TDM) of
biologicals will enhance TDM implementation in routine care and pharmacokinetic knowledge. …

Comparing tapering strategy to standard dosing regimen of tumor necrosis factor inhibitors in patients with spondyloarthritis in low disease activity

C Plasencia, EL Kneepkens, G Wolbink… - The Journal of …, 2015 - jrheum.org
Objective. To compare clinical outcomes, incidence of flares, and administered drug reduction
between patients with spondyloarthritis (SpA) under TNF inhibitor (TNFi) tapering strategy …

[HTML][HTML] Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study

…, AC Strang, J Kroon, LP Smits, EL Kneepkens… - Arthritis research & …, 2016 - Springer
Background Increasing numbers of patients (up to 40 %) with rheumatoid arthritis (RA)
achieve remission, yet it remains to be elucidated whether this also normalizes their …

The effects of 5-year etanercept therapy on cardiovascular risk factors in patients with psoriatic arthritis

R Agca, M Heslinga, EL Kneepkens… - The Journal of …, 2017 - jrheum.org
Objective. To investigate the effects of etanercept (ETN) on lipid metabolism and other known
cardiovascular disease (CVD) risk factors in patients with psoriatic arthritis (PsA). Methods. …