Older people suffer from a decline in immune system, which affects their ability to respond to
infections and to raise efficient responses to vaccines. Effective and specific antibodies in …

Background The complement system has a critical role in both the innate and the adaptive
immune responses. In humans, C3 exists as two main allotypes, F (fast) and S (slow), which …

OBJECTIVE: To determine the prevalence of sacroiliitis in patients who have back pain in
Crohn's disease (CD) using computed tomography (CT); and to reassess the association of …

Background & Aims: Recent studies suggest that major histocompatibility complex-encoded
susceptibility to primary sclerosing cholangitis (PSC) maps to the HLA B-TNFA region on …

Objectives: A single nucleotide polymorphism (SNP) of the gene encoding protein tyrosine
phosphatase type 22 (PTPN22 620W) has recently been described as a strong common …

Objectives. The initiating cause of Behçet's disease (BD) is unknown, but an aberrant response
to infection has been suggested. In this study, single nucleotide polymorphisms in Toll-…

Using polymerase chain reaction–sequence-specific primer (PCR-SSP) typing, this study
determined the frequency of human leukocyte antigen (HLA) DR- and -DQ alleles and …

Methods| Participants included 85 patients with IIU and 300 healthy, demographically matched
controls. Idiopathic intermediate uveitis was classified on the basis of ophthalmological …

Background. Antibody screening of a patient with a failed renal transplant showed positive
reactions with most, but not all HLA-Bw4-associated B-locus antigens. However, the patient’s …

… carried out by Dr Joo Wook Ahn and the HLA-C locus typing performed by Dr Elli Kondeatis. …