Background A phase 2 trial of tocilizumab showed preliminary evidence of efficacy in systemic
sclerosis. We assessed skin fibrosis and systemic sclerosis-associated interstitial lung …

Objective To investigate the efficacy and safety of ixekizumab in patients with active radiographic
axial spondyloarthritis (SpA) and prior inadequate response to or intolerance of 1 or 2 …

Background Ixekizumab, a high-affinity interleukin-17A (IL-17A) monoclonal antibody, has
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …

OBJECTIVE: To ascertain the prevalence of rheumatoid arthritis (RA) in Tucumán, Argentina.
METHODS: The study was conducted between January 1, 1998, and December 31, 1999, …

Background: The Health Assessment Questionnaire (HAQ) is one of the most frequently
used instruments to assess functional capacity in activities of daily living. Objective: The …

The goals of this study were to ascertain damage in patients with systemic lupus erythematosus
(SLE) from five rheumatologic centres in Argentina and to examine overall damage, …

Objective: Analyze disability determinants in a cohort of Argentine patients with rheumatoid
arthritis (RA). Material and Methods: Consecutive patients with RA, according to ACR'87 …

The aim of this study was to determine the prevalence and incidence of Systemic Lupus
Erythematosus (SLE) in Tucumán, Argentina. Methods: The study included inpatient and …

Objectives To validate the systemic lupus activity questionnaire (SLAQ) in Spanish language.
Methods The SLAQ questionnaire was translated and adapted in Spanish. Consecutive …

Background Blocking TNF alpha (TNFα) with monoclonal antibodies (mAbs) has been
successful in the treatment of rheumatoid arthritis. However primary and secondary resistances …