Variation in the safety of induced pluripotent stem cell lines
…, K Tanabe, M Ohnuki, D Ogawa, E Ikeda… - Nature …, 2009 - nature.com
We evaluated the teratoma-forming propensity of secondary neurospheres (SNS) generated
from 36 mouse induced pluripotent stem (iPS) cell lines derived in 11 different ways. …
from 36 mouse induced pluripotent stem (iPS) cell lines derived in 11 different ways. …
[PDF][PDF] Regulation of the HIF-1α level is essential for hematopoietic stem cells
Hematopoietic stem cells (HSCs) are sustained in a specific microenvironment known as
the stem cell niche. Mammalian HSCs are kept quiescent in the endosteal niche, a hypoxic …
the stem cell niche. Mammalian HSCs are kept quiescent in the endosteal niche, a hypoxic …
[PDF][PDF] Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells
…, A Nakamura-Ishizu, H Kobayashi, E Ikeda… - Cell stem cell, 2013 - cell.com
Defining the metabolic programs that underlie stem cell maintenance will be essential for
developing strategies to manipulate stem cell capacity. Mammalian hematopoietic stem cells (…
developing strategies to manipulate stem cell capacity. Mammalian hematopoietic stem cells (…
[HTML][HTML] Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells (∗)
Vascular endothelial growth factor (VEGF) is an endothelial specific angiogenic mitogen
secreted from various cell types including tumor cells. Increasing evidence suggests that VEGF …
secreted from various cell types including tumor cells. Increasing evidence suggests that VEGF …
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
…, M Koike, Y Uchiyama, E Ikeda… - Proceedings of the …, 2011 - National Acad Sciences
Once their safety is confirmed, human-induced pluripotent stem cells (hiPSCs), which do not
entail ethical concerns, may become a preferred cell source for regenerative medicine. Here…
entail ethical concerns, may become a preferred cell source for regenerative medicine. Here…
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury
…, Y Matsuzaki, M Yuzaki, E Ikeda… - Proceedings of the …, 2010 - National Acad Sciences
Various types of induced pluripotent stem (iPS) cells have been established by different
methods, and each type exhibits different biological properties. Before iPS cell-based clinical …
methods, and each type exhibits different biological properties. Before iPS cell-based clinical …
[HTML][HTML] Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165
G Hashimoto, I Inoki, Y Fujii, T Aoki, E Ikeda… - Journal of Biological …, 2002 - ASBMB
Vascular endothelial growth factor (VEGF), a potent angiogenic mitogen, plays a crucial role
in angiogenesis under various pathophysiological conditions. We have recently …
in angiogenesis under various pathophysiological conditions. We have recently …
Steps toward safe cell therapy using induced pluripotent stem cells
…, K Yoshida, Y Okada, O Tsuji, S Nori, E Ikeda… - Circulation …, 2013 - Am Heart Assoc
The enthusiasm for producing patient-specific human embryonic stem cells using somatic
nuclear transfer has somewhat abated in recent years because of ethical, technical, and …
nuclear transfer has somewhat abated in recent years because of ethical, technical, and …
Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis
M Jinzaki, A Tanimoto, M Mukai, E Ikeda… - Journal of computer …, 2000 - journals.lww.com
Purpose To correlate the enhancement pattern of double-phase helical computed
tomography (CT) of small renal parenchymal neoplasms with pathologic findings and tumor …
tomography (CT) of small renal parenchymal neoplasms with pathologic findings and tumor …
Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF‐induced angiogenesis
…, H Nakamura, K Makino, E Ikeda… - The FASEB …, 2002 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a strong angiogenic mitogen and plays
important roles in angiogenesis under various pathophysiological conditions. The in vivo …
important roles in angiogenesis under various pathophysiological conditions. The in vivo …