MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally
regulate gene expression by targeting the 3′ untranslated region (UTR) of specific …

… Cytoplasmic patterns were coordinated by Edward KL Chan (USA) and Carlos A. von …
leadership of Wilson de Melo Cruvinel and Edward KL Chan with input and consultation with all …

Toll-like receptors (TLRs) in innate immune cells are the prime cellular sensors for microbial
components. TLR activation leads to the production of proinflammatory mediators and thus …

Introduction MicroRNAs are small noncoding RNA molecules that negatively regulate gene
expression via degradation or translational repression of their targeted mRNAs. It is known …

Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for
the transformation of human cells. However, the molecular mechanisms by which PP2A …

Anti-nuclear antibodies (ANA) are fundamental for the diagnosis of autoimmune diseases,
and have been determined by indirect immunofluorescence assay (IIFA) for decades. As the …

The GW182 RNA-binding protein was initially shown to associate with a specific subset of
mRNAs and to reside within discrete cytoplasmic foci named GW bodies (GWBs) 1 . GWBs are …

On the basis of 2093 meioses analyzed in two separate intraspecific backcrosses, the location
of the mouseLps d mutation was circumscribed to a genetic interval 0.9 cM in size. A total …

The human toll-like receptor 4 (TLR4) pathway is activated in response to lipopolysaccharide
(LPS), and subsequent signal transductions lead to the production of cytokines such as …

Objective To estimate the prevalence, types, and sociodemographic and biobehavioral
correlates of antinuclear antibodies (ANAs) in the US. Methods We conducted a cross‐sectional …