Reduction of skin innervation is associated with a severe fibromyalgia phenotype

D Evdokimov, J Frank, A Klitsch… - Annals of …, 2019 - Wiley Online Library
Objective To assess patterns and impact of small nerve fiber dysfunction and pathology in
patients with fibromyalgia syndrome (FMS). Methods One hundred seventeen women with …

[HTML][HTML] CNS imaging characteristics in fibromyalgia patients with and without peripheral nerve involvement

HC Aster, D Evdokimov, A Braun, N Üçeyler, T Kampf… - Scientific reports, 2022 - nature.com
We tested the hypothesis that reduced skin innervation in fibromyalgia syndrome is associated
with specific CNS changes. This prospective case–control study included 43 women …

[HTML][HTML] Clustering fibromyalgia patients: A combination of psychosocial and somatic factors leads to resilient coping in a subgroup of fibromyalgia patients

A Braun, D Evdokimov, J Frank, P Pauli, N Üçeyler… - PLoS …, 2020 - journals.plos.org
Background Coping strategies and their efficacy vary greatly in patients suffering from
fibromyalgia syndrome (FMS). Objective We aimed to identify somatic and psychosocial factors …

Reduced association between dendritic cells and corneal sub‐basal nerve fibers in patients with fibromyalgia syndrome

A Klitsch, D Evdokimov, J Frank… - Journal of the …, 2020 - Wiley Online Library
In our study, we aimed at investigating corneal langerhans cells (LC) in patients with fibromyalgia
syndrome (FMS) and small fiber neuropathy (SFN) as potential contributors to corneal …

[HTML][HTML] Distinct CholinomiR blood cell signature as a potential modulator of the cholinergic system in women with fibromyalgia syndrome

…, S Lobentanzer, L Eisenberg, D Evdokimov… - Cells, 2022 - mdpi.com
Fibromyalgia syndrome (FMS) is a heterogeneous chronic pain syndrome characterized by
musculoskeletal pain and other key co-morbidities including fatigue and a depressed mood. …

Pain-associated mediators and axon pathfinders in fibromyalgia skin cells

D Evdokimov, L Kreß, P Dinkel, J Frank… - The Journal of …, 2020 - jrheum.org
Objective. To investigate whether the expression of cytokine, nociception-associated ion
channel, and axon guidance genes in patients with skin cell fibromyalgia syndrome (FMS) …

[HTML][HTML] MiR103a-3p and miR107 are related to adaptive coping in a cluster of fibromyalgia patients

A Braun, D Evdokimov, J Frank, C Sommer… - PLoS One, 2020 - journals.plos.org
Background MicroRNA (miRNA) mainly inhibit post-transcriptional gene expression of
specific targets and may modulate disease severity. Objective We aimed to identify miRNA …

Fibromyalgia vs small fiber neuropathy: diverse keratinocyte transcriptome signature

F Karl, T Bischler, N Egenolf, D Evdokimov, T Heckel… - Pain, 2021 - journals.lww.com
Damage to thinly myelinated and unmyelinated nerve fibers causes small fiber pathology,
which is increasingly found in pain syndromes such as small fiber neuropathy (SFN) and …

[HTML][HTML] Characterization of dermal skin innervation in fibromyalgia syndrome

D Evdokimov, P Dinkel, J Frank, C Sommer… - PLoS One, 2020 - journals.plos.org
Introduction We characterized dermal innervation in patients with fibromyalgia syndrome (FMS)
as potential contribution to small fiber pathology. Methods Skin biopsies of the calf were …

[HTML][HTML] Distinguishing fibromyalgia syndrome from small fiber neuropathy: a clinical guide

S Jänsch, D Evdokimov, N Egenolf… - Pain …, 2024 - journals.lww.com
Objective: To comprehensively investigate clinical characteristics of women with FMS and
SFN to determine clinically applicable parameters for differentiation. Methods: We …