Purpose Salvage chemotherapy followed by high-dose therapy and autologous stem-cell
transplantation (ASCT) is the standard treatment for relapsed diffuse large B-cell lymphoma (…

Background The MInT study was the first to show improved 3-year outcomes with the addition
of rituximab to a CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone)-like …

… Although all authors completed the disclosure declaration, the following author(s) and/or
an author's immediate family member(s) indicated a financial or other interest that is …

Purpose Thalidomide is effective in the treatment of newly diagnosed and relapsed/refractory
multiple myeloma (MM). However, the role of thalidomide in the post-autologous stem cell …

A sponsor of an Abbreviated New Drug Application (ANDA) must have information to show
that the proposed generic product and the innovator product are both pharmaceutically …

Impurities in drug substances and drug products have been important regulatory issues in
the Office of Generic Drugs by having significant impact on the approvability of Abbreviated …

Background Plant nutrition and climatic conditions play important roles on the growth and
secondary metabolites of stevia (Stevia rebaudiana Bertoni); however, the nutritional dose is …

In recent years, biopharmaceutical drug products have become hugely successful. However,
they are often complex molecules that are expensive to manufacture. Commercial needs …

The immunoglobulin new antigen receptors (IgNARs) are a class of Ig-like molecules of the
shark immune system that exist as heavy chain-only homodimers and bind antigens by their …

We report the laser operation of a thin-film waveguide structure grown by the pulsed laser
deposition technique. A 2.7-m-thick crystalline film of neodymium doped Gd3Ga5O12 Nd: …