User profiles for Desmond Y.H. Yap

Desmond Yat Hin Yap

Department of Medicine, The University of Hong Kong
Verified email at hku.hk
Cited by 3635

[HTML][HTML] B cell abnormalities in systemic lupus erythematosus and lupus nephritis—role in pathogenesis and effect of immunosuppressive treatments

DYH Yap, TM Chan - International journal of molecular sciences, 2019 - mdpi.com
Abnormalities in B cells play pivotal roles in the pathogenesis of systemic lupus erythematosus
(SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance mechanisms …

Recommendations by the Asian Pacific society of nephrology (APSN) on the appropriate use of HIF‐PH inhibitors

DYH Yap, LP McMahon, CM Hao, N Hu, H Okada… - …, 2021 - Wiley Online Library
Renal anaemia is a common and important complication in patients with chronic kidney
disease (CKD). The current standard‐of‐care treatment for renal anaemia in CKD patients …

[HTML][HTML] Pathogenesis of renal disease in systemic lupus erythematosus—the role of autoantibodies and lymphocytes subset abnormalities

DYH Yap, KN Lai - International journal of molecular sciences, 2015 - mdpi.com
Lupus nephritis (LN) is a common and severe organ manifestation of systemic lupus
erythematosus (SLE), and is associated with significant patient morbidity and mortality. …

Survival analysis and causes of mortality in patients with lupus nephritis

DYH Yap, CSO Tang, MKM Ma… - Nephrology Dialysis …, 2012 - academic.oup.com
Background This study aimed to define the causes and associated risks of death compared
with the local general population in Chinese patients with lupus nephritis in the recent era. …

Enhanced psychosocial support for caregiver burden for patients with chronic kidney failure choosing not to be treated by dialysis or transplantation: a pilot …

KY Chan, T Yip, DYH Yap, MK Sham, YC Wong… - American Journal of …, 2016 - Elsevier
Background Family caregivers of patients with chronic kidney failure have increased burden,
as reflected by their high frequency of physical and mental disturbances. The impact of …

Lupus nephritis in Asia: clinical features and management

DYH Yap, TM Chan - Kidney Diseases, 2015 - karger.com
Background: Lupus nephritis (LN) is a common and severe organ involvement manifesting
itself in systemic lupus erythematosus (SLE). There is a considerable difference in prevalence…

Overview of lupus nephritis management guidelines and perspective from A sia

CC Mok, DYH Yap, SV Navarra, Z Liu, M Zhao… - …, 2014 - Wiley Online Library
Lupus nephritis ( LN ) is a common and important manifestation of systemic lupus
erythematosus ( SLE ). Evidence suggests higher rates of lupus renal involvement in A sian …

Pilot 24 month study to compare mycophenolate mofetil and tacrolimus in the treatment of membranous lupus nephritis with nephrotic syndrome

DYH Yap, X Yu, XMEI CHEN, F Lu, N Chen… - …, 2012 - Wiley Online Library
Pilot 24 month study to compare mycophenolate mofetil and tacrolimus in the treatment of
membranous lupus nephritis with nephrotic syndrome - YAP - 2012 - Nephrology - Wiley …

Longterm data on sirolimus treatment in patients with lupus nephritis

DYH Yap, C Tang, GCW Chan, LPY Kwan… - The Journal of …, 2018 - jrheum.org
Objective. To expand the limited longterm data on sirolimus treatment in patients with lupus
nephritis (LN). Our pilot short-term data suggested efficacy of sirolimus treatment in these …

[HTML][HTML] MicroRNAs in lupus nephritis–role in disease pathogenesis and clinical applications

BYF So, DYH Yap, TM Chan - International journal of molecular sciences, 2021 - mdpi.com
MicroRNAs (miRs) are non-coding small RNAs that act as epigenetic modulators to regulate
the protein levels of target mRNAs without modifying the genetic sequences. The role of …