As patient and family engagement activity broadens across the continuum of care and expands
around the world, the question of compensation for an increasingly competent advisory …

Proteins often function as components of multi-subunit complexes. Despite its long history as
a model organism 1 , no large-scale analysis of protein complexes in Escherichia coli has …

The Strategy for Patient-Oriented Research Chronic Pain Network was founded in 2016 and
is a patient-oriented research network funded by the Canadian Institutes of Health Research…

As six patient partners in Canada, we aim to contribute to learning and to provide an opportunity
to reflect on patient engagement (PE) in research and healthcare environments. Patient …

Identification of protein–protein interactions often provides insight into protein function, and
many cellular processes are performed by stable protein complexes. We used tandem affinity …

Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA
polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 and …

Deletions of three yeast genes, SET2, CDC73, and DST1, involved in transcriptional elongation
and/or chromatin metabolism were used in conjunction with genetic array technology to …

Importance Extenuating circumstances can trigger unplanned changes to randomized trials
and introduce methodological, ethical, feasibility, and analytical challenges that can …

Background A 2017 systematic review suggested patient engagement in clinical trials has
been limited, with little active engagement in trial design or data analysis, interpretation or …

A remarkably large collection of evolutionarily conserved proteins has been implicated in
processing of noncoding RNAs and biogenesis of ribonucleoproteins. To better define the …