User profiles for David Saadoun
SAADOUNProfesseur de médecine interne Verified email at aphp.fr Cited by 26067 |
[HTML][HTML] Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis
D Saadoun, M Rosenzwajg, F Joly, A Six… - … England Journal of …, 2011 - Mass Medical Soc
Background Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced levels
of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of vasculitis …
of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of vasculitis …
Rituximab plus Peg-interferon-α/ribavirin compared with Peg-interferon-α/ribavirin in hepatitis C–related mixed cryoglobulinemia
D Saadoun, M Resche Rigon, D Sene… - Blood, The Journal …, 2010 - ashpublications.org
Abstract Treatment of hepatitis C (HCV)–mixed cryoglobulinemia (MC) may target either the
viral trigger (HCV) or the downstream B-cell clonal expansion. Prospective cohort study of …
viral trigger (HCV) or the downstream B-cell clonal expansion. Prospective cohort study of …
Antiviral therapy for hepatitis C virus–associated mixed cryoglobulinemia vasculitis: a long‐term followup study
D Saadoun, M Resche‐Rigon… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To evaluate the long‐term efficacy of anti–hepatitis C virus (HCV) therapy in
patients with HCV‐associated mixed cryoglobulinemia (HCV‐MC) vasculitis and to assess the …
patients with HCV‐associated mixed cryoglobulinemia (HCV‐MC) vasculitis and to assess the …
Mortality in Behçet's disease
D Saadoun, B Wechsler, K Desseaux… - Arthritis & …, 2010 - Wiley Online Library
Objective To report the long‐term mortality in patients with Behçet's disease (BD). Methods A
cohort of 817 patients fulfilling the international criteria for BD from a single center in France …
cohort of 817 patients fulfilling the international criteria for BD from a single center in France …
New insights into the pathogenesis of Behcet's disease
Behçet's disease (BD) is a recurrent systemic inflammatory disorder of unknown origin
characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of large …
characterized by oral and genital mucous ulcer, uveitis, and skin lesions. Involvement of large …
Extrahepatic manifestations of chronic hepatitis C virus infection
…, L Savey, AC Desbois, D Saadoun - Therapeutic …, 2016 - journals.sagepub.com
During hepatitis C virus (HCV) chronic infection, extrahepatic manifestations are frequent
and polymorphous. This article reports on a large cohort of patients with HCV-related …
and polymorphous. This article reports on a large cohort of patients with HCV-related …
[HTML][HTML] Behçet's disease physiopathology: a contemporary review
MJ Zeidan, D Saadoun, M Garrido, D Klatzmann… - Autoimmunity …, 2016 - Springer
Behçet’s disease, also known as the Silk Road Disease, is a rare systemic vasculitis disorder
of unknown etiology. Recurrent attacks of acute inflammation characterize Behçet’s disease…
of unknown etiology. Recurrent attacks of acute inflammation characterize Behçet’s disease…
2018 update of the EULAR recommendations for the management of Behçet's syndrome
Several new treatment modalities with different mechanisms of action have been studied in
patients with Behçet’s syndrome (BS). The aim of the current effort was to update the …
patients with Behçet’s syndrome (BS). The aim of the current effort was to update the …
Complement receptor 2/CD21− human naive B cells contain mostly autoreactive unresponsive clones
Complement receptor 2–negative (CR2/CD21 − ) B cells have been found enriched in patients
with autoimmune diseases and in common variable immunodeficiency (CVID) patients …
with autoimmune diseases and in common variable immunodeficiency (CVID) patients …
Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial
…, A Mekinian, E Regnier, D Saadoun… - Annals of the …, 2019 - ard.bmj.com
Objective Regulatory T cells (Tregs) prevent autoimmunity and control inflammation.
Consequently, any autoimmune or inflammatory disease reveals a Treg insufficiency. As low-dose …
Consequently, any autoimmune or inflammatory disease reveals a Treg insufficiency. As low-dose …