User profiles for David R.W. Jayne
 | David JayneProfessor of Clinical Autoimmunity, University of Cambridge Verified email at cam.ac.uk Cited by 74089 |
[HTML][HTML] KDIGO 2021 clinical practice guideline for the management of glomerular diseases
…, KL Gibson, RJ Glassock, DRW Jayne… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic autoimmune
diseases, infections, drugs, or malignancy, affects individuals of all ages. In most kidney …
diseases, infections, drugs, or malignancy, affects individuals of all ages. In most kidney …
[HTML][HTML] Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis
Background Cyclophosphamide induction regimens for antineutrophil cytoplasmic antibody
(ANCA)–associated vasculitis are effective in 70 to 90% of patients, but they are associated …
(ANCA)–associated vasculitis are effective in 70 to 90% of patients, but they are associated …
Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis
DRW Jayne, G Gaskin, N Rasmussen… - Journal of the …, 2007 - journals.lww.com
Systemic vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens (ANCA)
is the most frequent cause of rapidly progressive glomerulonephritis. Renal failure at …
is the most frequent cause of rapidly progressive glomerulonephritis. Renal failure at …
[HTML][HTML] Genetically distinct subsets within ANCA-associated vasculitis
…, JU Holle, RA Watts, DRW Jayne… - … England Journal of …, 2012 - Mass Medical Soc
Background Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a severe
condition encompassing two major syndromes: granulomatosis with polyangiitis (formerly …
condition encompassing two major syndromes: granulomatosis with polyangiitis (formerly …
[HTML][HTML] Executive summary of the KDIGO 2021 guideline for the management of glomerular diseases
…, FC Fervenza, KL Gibson, RJ Glassock, DRW Jayne… - Kidney international, 2021 - Elsevier
The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the
Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is …
Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is …
Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody—associated vasculitis: a randomized trial
K De Groot, L Harper, DRW Jayne… - Annals of internal …, 2009 - acpjournals.org
Background: Current therapies for antineutrophil cytoplasmic antibody (ANCA)–associated
vasculitis are limited by toxicity. Objective: To compare pulse cyclophosphamide with daily …
vasculitis are limited by toxicity. Objective: To compare pulse cyclophosphamide with daily …
Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody–associated vasculitis
…, WL Gross, R Luqmani, DRW Jayne - … : Official Journal of …, 2005 - Wiley Online Library
Objective Standard therapy for antineutrophil cytoplasmic antibody–associated systemic
vasculitis (AASV) with cyclophosphamide (CYC) and prednisolone is limited by toxicity. This …
vasculitis (AASV) with cyclophosphamide (CYC) and prednisolone is limited by toxicity. This …
Outcome of ANCA-associated renal vasculitis: a 5-year retrospective study
[Formula: see text] Renal involvement is frequently present in antineutrophil cytoplasmic
autoantibody (ANCA)-associated systemic vasculitis and is an important cause of end-stage …
autoantibody (ANCA)-associated systemic vasculitis and is an important cause of end-stage …
Mycophenolate mofetil vs azathioprine for remission maintenance in antineutrophil cytoplasmic antibody–associated vasculitis: a randomized controlled trial
…, KM Wissing, C Pagnoux, W Schmitt, DRW Jayne… - Jama, 2010 - jamanetwork.com
… Dr Jayne reported receiving research grant support from Aspreva (now Viforpharma) and
consulting fees and research grant support from Hoffman-La Roche. None of the other authors …
consulting fees and research grant support from Hoffman-La Roche. None of the other authors …
T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
EF McKinney, JC Lee, DRW Jayne, PA Lyons… - Nature, 2015 - nature.com
The clinical course of autoimmune and infectious disease varies greatly, even between
individuals with the same condition. An understanding of the molecular basis for this …
individuals with the same condition. An understanding of the molecular basis for this …