To identify novel genes associated with ALS, we undertook two lines of investigation. We
carried out a genome-wide association study comparing 20,806 ALS cases and 59,804 controls…

Small‐fiber neuropathy is a common disorder. It is often “idiopathic” and typically presents
with painful feet in patients over the age of 60. Autoimmune mechanisms are often suspected, …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are age-related
neurodegenerative disorders with shared genetic etiologies and overlapping clinical and …

An acute myopathy of intensive care occurs in critically ill patients treated with intravenous
corticosteroids and neuromuscular junction‐blocking agents. The full clinicopathological …

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in adults and
is characterized by neurodegeneration of motor neurons in the brain and spinal cord. The …

Objective To determine the long‐term outcome and associated clinical, serologic, and
pathologic features in a cohort of patients with connective tissue disease (CTD) and the anti–…

The spectrum of neuromuscular disorders among intensive care unit (ICU) patients has
shifted toward disorders acquired within the ICU and away from “traditional” neuromuscular …

Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motor neurons. We
tested the hypothesis that proteomic analysis will identify protein biomarkers that provide …

There is no effective treatment for amyotrophic lateral sclerosis (ALS), a devastating motor
neuron disease. However, discovery of a G 4 C 2 repeat expansion in the C9ORF72 gene as …

OBJECTIVE: Stereotactic radiosurgical treatment of the proximal trigeminal nerve is used to
relieve the pain of trigeminal neuralgia. The mechanism of the radiosurgical effect is not …