… 1.djhunter{at}durham.ac.uk Rather than exclude politics from health, David Hunter
argues that we must embrace it if we are to improve our complex health systems … David …

Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …

Statistics in Medicine — Reporting of Subgroup Analyses in Clinical Trials | NEJM Skip to main
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Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D)
and 38,987 controls of European descent and following up previously unidentified meta-…

Background The relation between body weight and overall mortality remains controversial
despite considerable investigation. Methods We examined the association between body-…

We conducted a genome-wide association study (GWAS) of breast cancer by genotyping
528,173 SNPs in 1,145 postmenopausal women of European ancestry with invasive breast …

Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

Background The effect of adding progestins to estrogen therapy on the risk of breast cancer
in postmenopausal women is controversial. Methods To quantify the relation between the …

Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of >12 million variants, …