Normotensive renal failure in systemic sclerosis

DJ Helfrich, B Banner, VD Steen… - Arthritis & Rheumatism …, 1989 - Wiley Online Library
Of 140 patients with “scleroderma renal crisis” encountered during a 33‐year period, 15 of
131 (11%) whose blood pressures were recorded were normotensive during this complication…

Childhood onset systemic sclerosis: classification, clinical and serologic features, and survival in comparison with adult onset disease.

…, T Arkachaisri, M Lucas, N Fertig, DJ Helfrich… - The Journal of …, 2006 - jrheum.org
OBJECTIVE: To describe the differences between patients with systemic sclerosis (SSc)
having childhood versus adult onset evaluated at a single medical center. METHODS: Patients …

Scleromyxedema myopathy: case report and review of the literature

DJ Helfrich, ER Walker, AJ Martinez… - … : Official Journal of the …, 1988 - Wiley Online Library
We describe a patient who had scleromyxedema associated with proximal myopathy. The
histopathologic and electron microscopic features are presented. In addition, we review the …

Clinical and radiographic improvement of bone of the second lumbar vertebra in Paget's disease following therapy with etidronate disodium: a case report

JJ Nicholas, DJ Helfrich, L Cooperstein… - … : Official Journal of …, 1989 - Wiley Online Library
Paget's disease of bone is most commonly seen in the spine; it may either be asymptomatic
or may cause pain and neurologic impairment. We describe a patient with back pain due to …

Pervasive personal computing in an internet suspend/resume system

…, DJ Farber, MA Kozuch, CJ Helfrich… - IEEE Internet …, 2007 - ieeexplore.ieee.org
The Internet suspend/resume model of mobile computing cuts the tight binding between PC
state and PC hardware. By layering a virtual machine on distributed storage, ISR lets the VM …

Preclinical characterization of A‐582941: A novel α7 neuronal nicotinic receptor agonist with broad spectrum cognition‐enhancing properties

…, S Halm, R Harris, RJ Helfrich… - CNS neuroscience & …, 2008 - Wiley Online Library
Among the diverse sets of nicotinic acetylcholine receptors (nAChRs), the α7 subtype is
highly expressed in the hippocampus and cortex and is thought to play important roles in a …

A cell-based microarrayed compound screening format for identifying agonists of G-protein-coupled receptors

…, JL Kofron, RJ Helfrich, E Gubbins, J McGowen… - Analytical …, 2003 - Elsevier
The identification of agonist and antagonist leads for G-protein-coupled receptors (GPCRs)
is of critical importance to the pharmaceutical and biotechnology industries. We report on the …

Structure–Activity Studies of Diazabicyclo [3.3. 0] octane-Substituted Pyrazines and Pyridines as Potent α4β2 Nicotinic Acetylcholine Receptor Ligands

…, DJ Anderson, RJ Helfrich, J Malysz… - Journal of medicinal …, 2011 - ACS Publications
A series of diazabicyclo[3.3.0]octane substituted pyridines and pyrazines was synthesized
and characterized at the α4β2 neuronal nicotinic acetylcholine receptor (nAChR). The …

Long nonlinear internal waves

KR Helfrich, WK Melville - Annu. Rev. Fluid Mech., 2006 - annualreviews.org
Over the past four decades, the combination of in situ and remote sensing observations has
demonstrated that long nonlinear internal solitary-like waves are ubiquitous features of …

The “Pope Scope”

J Helfrich - Wicazo Sa Review, 2019 - JSTOR
… As historian David J. Weber observed, “By placing their own sacred space in the superior
position, Spaniards made a powerful statement about the dominance of their religion, just as …