CD59 deficiency is a common finding in RBCs and WBCs in patients with chronic hemolysis
suffering from paroxysmal nocturnal hemoglobinuria in which the acquired mutation in the …

Background Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid
arthritis. The Oral Rheumatoid Arthritis triaL (ORAL) Strategy aimed to assess the comparative …

Infusion of either embryonic or mesenchymal stem cells prolongs the survival of organ
transplants derived from stem cell donors and prevents graft-versus-host-disease (GVHD). An in-…

Bacteria, such as Fusobacterium nucleatum, are present in the tumor microenvironment.
However, the immunological consequences of intra-tumoral bacteria remain unclear. Here, we …

Sepsis has no proven pharmacologic treatment other than appropriate antibiotic agents,
fluids, vasopressors as needed, and possibly corticosteroids. It is generally initiated mainly by …

During apoptotic cell death, cell surface ligands initiate phagocytosis of the dying cell.
Clearance of these apoptotic cells is thought to occur without an immune response. Since a …

Immature dendritic cells (iDCs) do not mature after uptake of apoptotic cells and may play a
role in the induction of peripheral tolerance to self antigens derived from apoptotic material. …

Background Approximately 5.1 million Israelis had been fully immunized against coronavirus
disease 2019 (Covid-19) after receiving two doses of the BNT162b2 messenger RNA …

Apoptotic cells are rapidly engulfed by phagocytes, but the receptors and ligands responsible
for this phenomenon are incompletely characterized. Previously described receptors on …

Human cytomegalovirus, a chief pathogen in immunocompromised people, can persist in a
healthy immunocompetent host throughout life without being eliminated by the immune …