Insulin-dependent diabetes mellitus is caused by autoimmune destruction of the insulin-producing
beta cells of the pancreas. The results described here indicate that a beta-cell target …

Background The registration trials of messenger RNA (mRNA) vaccines against SARS-CoV-2
did not address patients with inflammatory rheumatic diseases (IRD). Objective To assess …

OBJECTIVE: Adenosine exerts antiinflammatory effects via activation of the A3 adenosine
receptor (A3AR), a Gi protein-associated cell-surface receptor, overexpressed in synovial …

OBJECTIVE:. The treatment of rheumatoid arthritis (RA) has changed dramatically with the
introduction of anti-tumor necrosis factor (TNF) agents. Unfortunately, a subset of patients …

OBJECTIVES: To review pulmonary arteritis (PA) complicated by pulmonary arterial
hypertension (PAH) in Takayasu's arteritis (TA). METHODS: Two cases of PA and PAH in TA …

Background Pomegranate extract (POMx) consumption has been shown to reduce the
incidence and severity of collagen-induced arthritis in mice. Objectives To investigate whether …

Objective Sclerodactyly with acroosteolysis (AO) and calcinosis are prominent features of
systemic sclerosis (SSc), but the pathogenesis of these findings is poorly understood. Vitamin …

Rituximab (RTX) is a chimeric anti-CD20 antibody, approved for rheumatoid arthritis (RA)
patients who failed anti-Tumor Necrosis Factor therapy. It has been used occasionally for life-…

Objective We aimed to characterize the course of COVID-19 in autoimmune inflammatory
rheumatic disease (AIIRD) patients in Israel, taking into consideration several remarkable …

Oxidative stress is involved in pathogenesis of Raynaud’s phenomenon (RP), a hallmark of
systemic sclerosis (SSc). Frequent episodes of ischemia–reperfusion may lead to release of …