Reasons for performing study: Bisphosphonates, such as tiludronate, are used to normalise
bone metabolism via inhibition of bone resorption. Areas of increased bone resorption and …

Introduction The aim of this prospective, randomized, controlled, double-blind study was to
evaluate the effects of tiludronate (TLN), a bisphosphonate, on structural, biochemical and …

: In a review of 1037 patients with colorectal cancers, there were 32 patients below the age
of 40 years (3 percent). Rectal bleeding and abdominal pain were the most common …

Objective —To evaluate the efficacy of tiludronate for the treatment of horses with signs of
pain associated with lesions of the thoracolumbar vertebral column. Animals —29 horses with …

Objective. To investigate over a 1-year period in dogs that underwent extracapsular
stabilization surgery (ECS) following anterior cruciate ligament (ACL) transection: whether …

Low anterior resection with a stapled anastomosis is the operation of choice for almost all
rectal lesions in which the sphincter can be safely preserved. We have reported the results of a …

Background This retrospective study analyzes and compares the results of patients undergoing
carotid endarterectomy (CE) for atherosclerotic stenosis obtained by 2 surgeons during …

Two studies were conducted in order to assess the linearity and stationarity of the pharmacokinetics
of tiludronate in horses. For each study, plasma concentrations of tiludronate were …

Plasma and urine pharmacokinetics of tiludronate administered once daily as an intravenous
bolus of 0.1 mg/kg for ten consecutive days (group 1, n=6) was compared to a single slow …

Introduction Tiludronic acid as a bisphosphonate has a strong affinity for bone, making difficult
the assessment of its PK profile in this deep compartment on living animals. The invasive …