Effects of sodium oxybate on sleep physiology and sleep/wake-related symptoms in patients with fibromyalgia syndrome: a double-blind, randomized, placebo …

H Moldofsky, NH Inhaber, DR Guinta… - The Journal of …, 2010 - jrheum.org
Objective. To determine the effects of sodium oxybate (SXB) on sleep physiology and sleep/wake-related
symptoms in patients with fibromyalgia syndrome (FM). Methods. Of 304 …

Early replication and expression of oocyte-type 5S RNA genes in a Xenopus somatic cell line carrying a translocation.

DR Guinta, JY Tso, S Narayanswami… - Proceedings of the …, 1986 - National Acad Sciences
In Xenopus somatic cells, the somatic-type 5S RNA genes replicate early in S phase, bind
the transcription factor TFIIIA, and are expressed; in contrast, the late replicating oocyte-type …

Differential Order of Replication of Xenopus laevis 5S RNA Genes

DR Guinta, LJ Korn - Molecular and cellular biology, 1986 - Taylor & Francis
In Xenopus laevis there are two multigene families of 5S RNA genes: the oocyte-type 5S
RNA genes which are expressed only in oocytes and the somatic-type 5S RNA genes which …

[HTML][HTML] Long-term tolerability and maintenance of therapeutic response to sodium oxybate in an open-label extension study in patients with fibromyalgia

…, C Alegre, S Perrot, YG Wang, DR Guinta… - Arthritis Research & …, 2013 - Springer
Introduction The long-term safety and therapeutic response of sodium oxybate (SXB) in
fibromyalgia syndrome (FM) patients were assessed for a combined period of up to 1 year in a …

PURIFICATION, PROPERTIES, AND FUNCTION OF A BACTERIOPHAGE N4 EXONUCLEASE.

DR Guinta - 1983 - search.proquest.com
DIANE ROSE GUINTA CHICAGO, ILLINOIS MARCH, 1983 r * . ,.da ?' • Ml or cœrerrs
EXONUCLEASE tKLMSE IS REQUIRED FOR IN VITRO N4 WLICATION..................................................…

Increased mortality in narcolepsy

MM Ohayon, J Black, C Lai, M Eller, D Guinta… - Sleep, 2014 - academic.oup.com
Guinta, Lai and Eller are employees of Jazz Pharmaceuticals. Dr. Black is a part-time …
Ohayon, Jed Black, Chinglin Lai, Mark Eller, Diane Guinta, Arun Bhattacharyya, Increased Mortality …

Sodium oxybate reduces pain, fatigue, and sleep disturbance and improves functionality in fibromyalgia: results from a 14-week, randomized, double-blind, placebo …

…, TJ Swick, S Alvarez-Horine, YG Wang, D Guinta… - Pain, 2011 - Elsevier
This 14-week, phase 3, double-blind, randomized, controlled trial evaluated sodium oxybate
(SXB) 4.5 and 6g per night versus placebo in patients with fibromyalgia (FM). SXB is the …

Treatment of paediatric narcolepsy with sodium oxybate: a double-blind, placebo-controlled, randomised-withdrawal multicentre study and open-label investigation

…, J Black, R Parvataneni, D Guinta… - The Lancet Child & …, 2018 - thelancet.com
Background Narcolepsy is a lifelong neurological disorder with onset commonly in childhood
or adolescence. No drugs are indicated for cataplexy and excessive daytime sleepiness in …

Effect of sodium oxybate on disrupted nighttime sleep in patients with narcolepsy

T Roth, Y Dauvilliers, D Guinta… - Journal of sleep …, 2017 - Wiley Online Library
This post hoc analysis evaluated the dose‐related effects of sodium oxybate on sleep
continuity and nocturnal sleep quality in patients with narcolepsy–cataplexy. Polysomnography …

Long-term safety and maintenance of efficacy of sodium oxybate in the treatment of narcolepsy with cataplexy in pediatric patients

…, C Ruoff, J Black, R Parvataneni, D Guinta… - Journal of Clinical …, 2022 - jcsm.aasm.org
Guinta are former employees of Jazz Pharmaceuticals who, in the course of this employment,
received stock options exercisable for, and other stock awards of, ordinary shares of Jazz …