Acute‐on‐chronic liver failure (ACLF) in cirrhosis is characterized by acute decompensation
(AD), organ failure(s), and high short‐term mortality. Recently, we have proposed (systemic …

There is increasing evidence that the physical environment is a critical mediator of tumor
behavior. Hepatocellular carcinoma (HCC) develops within an altered biomechanical …

Acute‐on‐chronic liver failure (ACLF) is characterized by acute decompensation (AD) of
cirrhosis, organ failure(s), and high 28‐day mortality. We investigated whether assessments of …

Background & Aims Acute-on-chronic liver failure (ACLF), which develops in patients with
cirrhosis, is characterized by intense systemic inflammation and organ failure(s). Because …

Recruitment of polymorphonuclear neutrophils (PMNs) remains a paramount prerequisite in
innate immune defense and a critical cofounder in inflammatory vascular disease. …

ADAMTS13 is a circulating zinc metalloprotease that cleaves the hemostatic glycoprotein von
Willebrand factor (VWF) in a shear-dependent manner. Deficiency in ADAMTS13, owing to …

The emergence of resistance to imatinib (IM) mediated by mutations in the BCR-ABL domain
has become a major challenge in the treatment of chronic myeloid leukemia (CML). Here, …

We simultaneously transduced cells with three lentiviral gene ontology (LeGO) vectors
encoding red, green or blue fluorescent proteins. Individual cells were thereby marked by …

Transplantation of healthy cells to repair organ damage or replace deficient functions
constitutes a major goal of cell therapy. However, the mechanisms by which transplanted cells …

Intestinal inflammation can impair mucosal healing, thereby establishing a vicious cycle
leading to chronic inflammatory bowel disease (IBD). However, the signaling networks driving …