OBJECTIVE: To describe the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K),
a modification of SLEDAI to reflect persistent, active disease in those descriptors …

… Dominique Ibañez… Gladman, and Ms Ibañez had full access to all of the data in the study
and take responsibility for the integrity of the data and the accuracy of the data analysis. …

Objective Because women with systemic lupus erythematosus (SLE) are 5–8 times more
likely to develop coronary heart disease (CHD) than are women in the general population, we …

Objective Survival of patients with systemic lupus erythematosus (SLE) has improved
significantly, but new morbidities have emerged, leading to altered patterns of outcome in this …

OBJECTIVE: To determine the pattern of accumulation of damage in an inception cohort of
patients with systemic lupus erythematosus (SLE) followed yearly for at least 15 years, and to …

After fertilization, the quiescent zygote experiences a burst of genome activation that initiates
a short-lived totipotent state. Understanding the process of totipotency in human cells would …

Objective We describe disease activity, damage, and the accrual of key autoantibodies in
an inception systemic lupus erythematosus (SLE) cohort. Methods The Systemic Lupus …

Objectives Coronavirus disease 2019 (COVID-19) survivors are reporting residual
abnormalities after discharge from hospital. Limited information is available about this stage of …

OBJECTIVE: To determine prevalence and type of atherosclerotic vascular events (AVE)
occurring after entry to the University of Toronto Lupus Clinic; and to compare risk factors in …

Objective To determine whether quality of life in patients with systemic lupus erythematosus
(SLE) measured by the Short Form 36 (SF‐36) changes over time and which patient‐ and …