Objective. To standardize outcome measures in systemic lupus erythematosus (SLE). Three
indices were identified which could adequately describe outcome (disease activity, damage …

A comment on this article appears in" Patient-reported outcome measures in arthroplasty
registries Report of the Patient-Reported Outcome Measures Working Group of the …

Pilot studies for phase III trials - which are comparative randomized trials designed to
provide preliminary evidence on the clinical efficacy of a drug or intervention - are routinely …

Background. The Health Utilities Index Mark 3 (HUI3) is a generic multiattribute preference-based
measure of health status and health-related quality of life that is widely used as an …

Objective. To test the reliability of the Systemic Lupus International Collaborating Clinics/American
College of Rheumatology (SLICC/ACR) Damage Index and the Systemic Lupus …

Background Sensitivity analyses play a crucial role in assessing the robustness of the findings
or conclusions based on primary analyses of data in clinical trials. They are a critical way …

Background Neck disorders are common, disabling and costly. The effectiveness of exercise
as a physiotherapy intervention remains unclear. Objectives To improve pain, disability, …

Study Design. A randomized, parallel-group, single-blinded clinical trial was performed.
After a 1-week baseline period, patients were randomized to 11 weeks of therapy, with …

Objective: To review the efficacy of conservative management of mechanical neck disorders.
Methods: Published and unpublished reports were identified through computerised and …

Manual therapy is often used with exercise to treat neck pain. This cervical overview group
systematic review update assesses if manual therapy, including manipulation or mobilisation, …