Objective. To analyse the clinical relevance of the production of anti-infliximab antibodies (anti-infliximab
Abs) in patients with RA undergoing infliximab treatment over a prolonged …

Background Infliximab (IFX) is a monoclonal antibody against tumour necrosis factor α that is
effective for treating spondyloarthritis (SpA). However, after initial success of the drug some …

Objectives The aim of this study was to determine whether antibodies to infliximab (IFX) in
Remicade-treated patients cross-react with the biosimilar CT-P13. Methods 250 consecutive …

Introduction Circulating CD4 T cells expressing CXCR5, ICOS and/or PD-1 are counterparts
of follicular helper T cells (Tfh). There are three subpopulations of circulating Tfh (cTfh): …

Introduction Anti-TNF drugs have proven to be effective against spondyloarthritis (SpA),
although 30% of patients fail to respond or experience adverse events leading to treatment …

Objectives To describe the frequency and causes for the presence of a halo sign on the
ultrasound of patients without a diagnosis of GCA. Methods In total, 305 patients with temporal …

Background Biological therapies have improved the clinical course and quality of life of
rheumatoid arthritis (RA) patients. Despite the availability and effectiveness of these treatments, …

Tumour necrosis factor inhibitors (TNFi) are effective in the majority of patients with rheumatoid
arthritis (RA), 1 however, an important reason for non-response is low drug level due to …

Objective. To compare clinical outcomes, incidence of flares, and administered drug reduction
between patients with spondyloarthritis (SpA) under TNF inhibitor (TNFi) tapering strategy …

Introduction: In our hospital, the detection of anti-TNF and anti-drug antibody levels are
used in clinical practice and can aim the clinicians to provide a safe and an efficient therapy. …