Background The epidemiological, prognostic, and therapeutic features of child and adolescent
meningioma are poorly defined. Clinical knowledge has been drawn from small case …

Medulloblastoma is curable in approximately 70 % of patients. Over the past decade,
progress in improving survival using conventional therapies has stalled, resulting in reduced …

With improvement in leukemia therapy, central nervous system (CNS) tumors are the leading
cause of cancer mortality in children and the most expensive of all human neoplasms to …

Connective tissue growth factor (CTGF/CCN2) has long been associated with human cancers.
The role it plays in these neoplasms is diverse and tumour specific. Recurring patterns in …

Background The relationship between histological chorioamnionitis and haematological
and biochemical markers in mothers and infants at delivery, and in infants postnatally, is …

Adolescent and young adult (AYA) survivors of pediatric oncology related cerebral insult are
vulnerable to numerous treatment-induced deficits that significantly enhance cardiovascular …

BACKGROUND Children receiving immunosuppressive treatment for cancer are at high risk
for invasive pneumococcal disease. The 13‐valent pneumococcal conjugate vaccine (…

Influenza is associated with significant morbidity and mortality in children receiving therapy
for cancer, yet recommendation for, and uptake of the seasonal vaccine remains poor. One …

BACKGROUND The extent of initial surgical resection has been identified as the strongest
prognostic indicator for survival in child and adolescent meningioma. Given the paucity of …

Relapse in pediatric T-cell acute lymphoblastic leukemia (T-ALL) remains a significant
clinical problem and is thought to be associated with clonal selection during treatment. In this …