We used the Immunochip array to analyze 2,816 individuals with juvenile idiopathic arthritis
(JIA), comprising the most common subtypes (oligoarticular and rheumatoid factor–negative …

Objective Blau syndrome and its sporadic counterpart, early‐onset sarcoidosis, share an
identical phenotype featuring the classic triad of arthritis, dermatitis, and uveitis and are …

Blau syndrome is a monogenic disease resulting from mutations in the pattern recognition
receptor NOD2, and is phenotypically characterized by the triad of granulomatous polyarthritis…

BACKGROUND AND OBJECTIVE: Recent evidence has linked childhood antibiotic use and
microbiome disturbance to autoimmune conditions. This study tested the hypothesis that …

Objective To test for associations between non–major histocompatibility complex susceptibility
loci previously reported in autoimmune diseases and juvenile idiopathic arthritis (JIA). …

Objective. To report baseline articular, functional and ocular findings of the first international
prospective cohort study of Blau syndrome (BS). Methods. Three-year, multicentre, …

Objective To determine the prevalence and outcome of chronic uveitis in patients with
juvenile rheumatoid arthritis (JRA). Methods A retrospective analysis of 760 patients with JRA …

Patients with sporadic early-onset granulomatous arthritis are clinically identical to Blau
syndrome, but without the family history. Blau syndrome is an autosomal dominant inherited …

Objective To study the phenotype characteristics of the largest to date cohort of patients with
pediatric granulomatous arthritis (PGA) and documented mutations in the NOD2 gene. …

Monocytes and macrophages are innate immune cells with diverse functions ranging from
phagocytosis of microorganisms to forming a bridge with the adaptive immune system. A …