Background Adolescents are increasingly susceptible to obesity, and thus at risk of later non-communicable
diseases, due to changes in food choices, physical activity levels and …

Objective Our aim was to assess the safety of cyclooxygenase-2 (COX-2) inhibitors in the
management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized, …

Background Primary ciliary dyskinesia (PCD) is a heterogeneous inherited disorder caused
by mutations in approximately 50 cilia-related genes. PCD genotype–phenotype …

Objective We aimed to assess the safety of opioids in the management of osteoarthritis (OA)
in a systematic review and meta-analysis of randomized, placebo-controlled trials. Methods …

Objective To assess the association between occupational exposures and knee osteoarthritis
(OA). Methods We systematically searched for observational studies that examined the …

Background: poor physical performance (PP) is known to be associated with disability, lower
quality of life and higher mortality rates. Knee and hip osteoarthritis (OA) might be expected …

Background the first quality of life questionnaire specific to sarcopenia, the SarQoL ® , has
recently been developed and validated in French. To extend the availability and utilisation of …

OBJECTIVE It is unclear whether people with and without diabetes equally benefitted from
reductions in cardiovascular disease (CVD). We aimed to compare recent trends in hospital …

Background Significant correlation has been previously demonstrated between radiographic
and clinical diagnoses of knee osteoarthritis (OA); however, the specific findings on clinical …

Objective Epidemiological studies of knee osteoarthritis (OA) have often used a radiographic
definition. However, the clinical syndrome of OA is influenced by a broad range of factors in …