Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (N-BNP) concentrations

RW Troughton, CM Frampton, TG Yandle, EA Espine… - The Lancet, 2000 - thelancet.com
Background There is currently no objective practical guide to intensity of drug treatment for
individuals with heart failure. We hypothesised that pharmacotherapy guided by plasma …

B-type natriuretic peptides and ejection fraction for prognosis after myocardial infarction

…, JG Lainchbury, RW Troughton, J Elliott, C Frampton… - Circulation, 2003 - Am Heart Assoc
Background— A recent landmark report has demonstrated that plasma B-type natriuretic
peptide (BNP) measured in acute coronary syndromes independently predicts mortality, heart …

Three psychotherapies for anorexia nervosa: a randomized, controlled trial

…, CM Bulik, CMA Frampton… - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: Few randomized, controlled trials have examined the efficacy of treatments for
anorexia nervosa. Cognitive behavior therapy and interpersonal psychotherapy are effective …

A double‐blind, placebo‐controlled study to assess the mitochondria‐targeted antioxidant MitoQ as a disease‐modifying therapy in Parkinson's disease

…, FL Rolfe, MM Lockhart, CM Frampton… - Movement …, 2010 - Wiley Online Library
Multiple lines of evidence point to mitochondrial oxidative stress as a potential pathogenic
cause for Parkinson's disease (PD). MitoQ is a powerful mitochondrial antioxidant. It is …

Brain natriuretic peptide and n-terminal brain natriuretic peptide in the diagnosis of heart failure in patients with acute shortness of breath

JG Lainchbury, E Campbell, CM Frampton… - Journal of the American …, 2003 - jacc.org
Objectives : This study sought to compare the utility of measurement of plasma brain natriuretic
peptide (BNP) and N-terminal brain natriuretic peptide (N-BNP) in the diagnosis of heart …

Physicochemical characterization of the orthorhombic polymorph of paracetamol crystallized from solution

G Nichols, CS Frampton - Journal of pharmaceutical sciences, 1998 - Wiley Online Library
This paper describes a method for the laboratory‐scale crystallization of the orthorhombic
polymorph (form II) of paracetamol (acetaminophen) from solution. Its structure has been …

N-terminal pro–B-type natriuretic peptide-guided treatment for chronic heart failure: results from the BATTLESCARRED (NT-proBNP–Assisted Treatment To Lessen …

…, RW Troughton, KM Strangman, CM Frampton… - Journal of the American …, 2009 - jacc.org
Objectives : The purpose of this study was to compare the effects of N-terminal pro–B-type
natriuretic peptide (NT-proBNP)-guided therapy with those of intensive clinical management …

Short-term outcomes of the Australasian randomized clinical study comparing laparoscopic and conventional open surgical treatments for colon cancer: the ALCCaS …

PJ Hewett, RA Allardyce, PF Bagshaw, CM Frampton… - 2008 - journals.lww.com
Background: Laparoscopy has revolutionized many abdominal surgical procedures.
Laparoscopic colectomy has become increasingly popular. The short-and long-term benefits and …

Long‐term results of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate: results at 7 years

…, CJ King, AM Westenberg, CM Frampton… - BJU …, 2012 - Wiley Online Library
Study Type – Therapy (RCT) Level of Evidence 1b What's known on the subject? and What
does the study add? HoLEP has been widely adopted worldwide as an alternative to TURP …

The mitochondria‐targeted anti‐oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

…, M Gibson, MM Lockhart, CM Frampton… - Liver …, 2010 - Wiley Online Library
Background: Increased oxidative stress and subsequent mitochondrial damage are important
pathways for liver damage in chronic hepatitis C virus (HCV) infection; consequently, …